80557-12-6 Usage
Description
Grifolic acid is a selective partial GPR120 agonist, a type of fatty acid receptor modulator. It is known for its ability to induce ERK and [Ca2+]i responses in cells expressing GPR120, while having no effects on those expressing GPR40. This unique characteristic makes it a promising candidate for various applications in different industries.
Uses
Used in Pharmaceutical Industry:
Grifolic acid is used as a selective partial GPR120 agonist for its potential therapeutic applications. Its ability to modulate ERK and [Ca2+]i responses in cells expressing GPR120 makes it a promising candidate for the development of drugs targeting specific diseases and conditions.
Used in Drug Discovery and Development:
Grifolic acid is used as a research tool in drug discovery and development. Its unique interaction with GPR120 and lack of effect on GPR40 allows researchers to study the role of these receptors in various biological processes and identify potential therapeutic targets.
Used in Nutritional Supplements:
Grifolic acid may be used as a nutritional supplement to support healthy metabolic function. Its agonistic effect on GPR120 could potentially contribute to improved insulin sensitivity and glucose metabolism, making it a valuable addition to dietary supplements for individuals seeking to maintain optimal health.
Check Digit Verification of cas no
The CAS Registry Mumber 80557-12-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,5,5 and 7 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 80557-12:
(7*8)+(6*0)+(5*5)+(4*5)+(3*7)+(2*1)+(1*2)=126
126 % 10 = 6
So 80557-12-6 is a valid CAS Registry Number.
80557-12-6Relevant articles and documents
Meroterpenoid total synthesis: Conversion of geraniol and farnesol into amorphastilbol, grifolin and grifolic acid by dioxinone-β-keto-acylation, palladium catalyzed decarboxylative allylic rearrangement and aromatization
Ma, Tsz-Kan,White, Andrew J.P.,Barrett, Anthony G.M.
supporting information, p. 2765 - 2767 (2017/06/23)
Biomimetic total syntheses of resorcinols amorphastilbol, grifolin and grifolic acid have been completed in four steps starting from geraniol and farnesol without the use of phenolic protection. The key steps involve C-acylation of dioxinone-β-keto esters, followed by palladium catalyzed decarboxylative allylic rearrangement and biomimetic aromatization.