8003-05-2 Usage
Description
Phenylmercuric nitrate is a mercury-based organic compound characterized by its white powder form. It possesses potent antibacterial and antifungal properties, which make it a valuable antimicrobial agent. Additionally, it serves as an effective preservative for parenteral injections, ensuring the sterility and safety of these medical products.
Uses
Used in Pharmaceutical Industry:
Phenylmercuric nitrate is used as a pharmaceutic aid for its antimicrobial properties. It plays a crucial role in preventing the growth of bacteria and fungi in various pharmaceutical products, thereby maintaining their efficacy and safety for use.
Used in Tree Wound Dressing:
In the agricultural sector, particularly for the care of trees, phenylmercuric nitrate serves as a tree wound dressing. It is applied to the injured or pruned areas of trees to prevent infections and promote healing. The antimicrobial activity of phenylmercuric nitrate helps protect the tree from potential diseases and decay that could arise from exposed wounds.
Used as a Preservative for Parenteral Injections:
Phenylmercuric nitrate is utilized as a preservative in the production of parenteral injections. Its inclusion ensures that the injections remain sterile and free from contamination, which is critical for maintaining the safety and effectiveness of these medical treatments.
Clinical Use
Phenylmercuric nitrate is a mixture of phenylmercuric nitrateand phenylmercuric hydroxide. It occurs as a whitecrystalline material that is sparingly soluble in water andslightly soluble in alcohol. It is used in concentrations of1:10,000 to 1:50,000 to preserve injectable drugs againstbacterial contamination. A disadvantage to organomercurialsis that their bacteriostatic efficacy is reduced in the presenceof serum.
Purification Methods
When recrystallised from water or aqueous EtOH, it has m 191-191.5o, and from 95% EtOH it has m 186.5o [Challanger & Rothstein J Chem Soc I 1258 1934]. When recrystallised from *C6H6 or CHCl3, it has m 131-131.5o [Morton et al. J Am Chem Soc 69 908 1947.] [Beilstein 16 III 1348, 16 IV 1721.]
Check Digit Verification of cas no
The CAS Registry Mumber 8003-05-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 8,0,0 and 3 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 8003-05:
(6*8)+(5*0)+(4*0)+(3*3)+(2*0)+(1*5)=62
62 % 10 = 2
So 8003-05-2 is a valid CAS Registry Number.
InChI:InChI=1/2C6H5.2Hg.NO3.H2O/c2*1-2-4-6-5-3-1;;;2-1(3)4;/h2*1-5H;;;;1H2/q;;;;-1;/r2C6H5Hg.NO3.H2O/c2*7-6-4-2-1-3-5-6;2-1(3)4;/h2*1-5H;;1H2/q;;-1;