79995-67-8

Basic information

• Product Name: 4H-1-Benzopyran-4-one, 2,3-dihydro-3,5-dihydroxy-2-(3-hydroxy-4-methox yphenyl)-7-methoxy-, (2R,3R)-
• Synonyms: 4H-1-Benzopyran-4-one, 2,3-dihydro-3,5-dihydroxy-2-(3-hydroxy-4-methox yphenyl)-7-methoxy-, (2R,3R)-;BluMeatin B
• CAS NO: 79995-67-8
• Molecular Formula: C17H16O7
• Molecular Weight: 332.3
• Mol File: 79995-67-8.mol
• Article Data: 1

Chemical Properties

• Melting Point: 165-167 °C
• Boiling Point: 627.8°C at 760 mmHg
• Flash Point: 234.4°C
• Appearance: /
• Density: 1.445g/cm³
• Vapor Pressure: 1.26E-16mmHg at 25°C
• Refractive Index: 1.644
• PKA: 7.24±0.60(Predicted)
• CAS DataBase Reference: 4H-1-Benzopyran-4-one, 2,3-dihydro-3,5-dihydroxy-2-(3-hydroxy-4-methox yphenyl)-7-methoxy-, (2R,3R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1-Benzopyran-4-one, 2,3-dihydro-3,5-dihydroxy-2-(3-hydroxy-4-methox yphenyl)-7-methoxy-, (2R,3R)-(79995-67-8)
• EPA Substance Registry System: 4H-1-Benzopyran-4-one, 2,3-dihydro-3,5-dihydroxy-2-(3-hydroxy-4-methox yphenyl)-7-methoxy-, (2R,3R)-(79995-67-8)

Safety Data

• Hazardous Substances Data: 79995-67-8(Hazardous Substances Data)

Usage

General Description

Benzopyran-4-one, 2,3-dihydro-3,5-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-methoxy- (2R,3R) is a chemical compound that belongs to the class of benzopyrans, which are heterocyclic compounds containing a benzene ring fused to a pyran ring. This specific compound is a derivative of 4H-1-benzopyran-4-one, with two hydroxyl groups at positions 3 and 5 of the pyran ring, and a hydroxyl and methoxy group attached to the phenyl ring at position 3. It is a chiral compound, with the (2R,3R) designation indicating the stereochemistry of the molecule. 4H-1-Benzopyran-4-one, 2,3-dihydro-3,5-dihydroxy-2-(3-hydroxy-4-methox yphenyl)-7-methoxy-, (2R,3R)- has potential biological activities and is of interest in the development of pharmaceuticals and natural products.

InChI:InChI=1/C17H16O7/c1-22-9-6-11(19)14-13(7-9)24-17(16(21)15(14)20)8-3-4-12(23-2)10(18)5-8/h3-7,16-19,21H,1-2H3/t16-,17+/m0/s1

Upstream product

• 186581-53-3 diazomethane 
• 480-18-2 taxifolin 

Relevant articles and documents

Structure-activity relationship for (+)-taxifolin isolated from silymarin as an inhibitor of amyloid β aggregation

Silymarin, the seed extract of Silybium marianum, has preventive effects against Alzheimer's disease-like pathogenesis in vivo. We isolated (+)-taxifolin (4) from silymarin as an inhibitor of aggregation of the 42- residue amyloid -protein. Structure-activity relationship studies revealed the 30,40-dihydroxyl groups to be critical to the anti-aggregative ability, whereas the 7-hydroxyl group and the stereochemistry at positions 2 and 3 were not important.