79352-66-2

Basic information

• Product Name: 4-(benzyloxy)-2-bromophenol
• Synonyms: 4-(benzyloxy)-2-bromophenol
• CAS NO: 79352-66-2
• Molecular Formula: C₁₃H₁₁BrO₂
• Molecular Weight: 279.12924
• EINECS: -0
• Mol File: 79352-66-2.mol
• Article Data: 9

Chemical Properties

• Melting Point: 72-73 °C(Solv: ligroine (8032-32-4))
• Boiling Point: 370.0±27.0 °C(Predicted)
• Appearance: /
• Density: 1.478±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 8.79±0.20(Predicted)
• CAS DataBase Reference: 4-(benzyloxy)-2-bromophenol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(benzyloxy)-2-bromophenol(79352-66-2)
• EPA Substance Registry System: 4-(benzyloxy)-2-bromophenol(79352-66-2)

Safety Data

• Hazardous Substances Data: 79352-66-2(Hazardous Substances Data)

Usage

Description

4-(Benzyloxy)-2-bromophenol is an organic compound characterized by the presence of a benzyloxy group attached to the 4-position and a bromine atom at the 2-position of a phenol molecule. This unique structure endows it with specific chemical properties that make it a valuable intermediate in the synthesis of various pharmaceutical compounds.

Uses

Used in Pharmaceutical Synthesis:
4-(Benzyloxy)-2-bromophenol is used as an intermediate in the synthesis of (S)-4-Hydroxy Penbutolol Hydrochloride (H948945), a hydroxylated metabolite of Penbutolol (P220500). This intermediate plays a crucial role in the production of pharmaceuticals, contributing to the development of medications with potential therapeutic benefits.

Upstream product

• 103-16-2 4-Benzyloxyphenol 
• 121767-81-5 4-Benzyloxy-2-bromo-1-(2-chloro-ethoxy)-benzene 

Downstream Products

• 121767-81-5 4-Benzyloxy-2-bromo-1-(2-chloro-ethoxy)-benzene 
• 79352-65-1 1-benzyloxy-3-bromo-4-methoxybenzene 
• 299917-34-3 5-Benzyloxy-2-methoxymethyloxy-1-bromobenzene 
• 816456-33-4 4-benzyloxy-2-(2H₃)-methylphenol 
• 835613-28-0 4-benzyloxy-1-methoxymethoxy-2-(D₃)methylbenzene 
• 835613-30-4 6-O-benzyl-(8-D3)-(all-rac)-δ-tocopherol 
• 123164-53-4 cordiachromene 
• 291772-25-3 6-benzyloxy-2-methyl-2-(4-methylpent-3-enyl)-2H-1-benzopyran 
• 299917-65-0 2-(5-Benzyloxy-2-hydroxyphenyl)pyridine 
• 299917-53-6 2-(5-Benzyloxy-2-methoxymethylphenyl)pyridine 
• 299917-55-8 C₁₇H₂₁BO₅ 

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