77988-07-9 Usage
Description
Secologanin diMethyl acetal is a naturally occurring compound derived from the leaves of Davidia involucrata, a plant species native to China. It is known for its unique chemical structure and potential biological activities, making it a subject of interest in various research fields.
Uses
Used in Pharmaceutical Industry:
Secologanin diMethyl acetal is used as a precursor in the synthesis of complex natural products and pharmaceutical compounds. Its unique structure allows for the development of novel drugs with potential applications in various therapeutic areas.
Used in Neuropharmacology:
Secologanin diMethyl acetal is used as a neuritogenic agent for promoting the growth and development of nerve cells (neurons) in PC12h cells. This property makes it a promising candidate for the development of treatments for neurological disorders and injuries.
Used in Natural Product Synthesis:
Secologanin diMethyl acetal is used as a key intermediate in the synthesis of various natural products, including those with potential medicinal properties. Its versatility in chemical reactions enables the creation of a wide range of bioactive compounds for further research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 77988-07-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,9,8 and 8 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 77988-07:
(7*7)+(6*7)+(5*9)+(4*8)+(3*8)+(2*0)+(1*7)=199
199 % 10 = 9
So 77988-07-9 is a valid CAS Registry Number.
InChI:InChI=1/C19H30O11/c1-5-9-10(6-13(25-2)26-3)11(17(24)27-4)8-28-18(9)30-19-16(23)15(22)14(21)12(7-20)29-19/h5,8-10,12-16,18-23H,1,6-7H2,2-4H3/t9-,10+,12-,14-,15+,16-,18+,19+/m1/s1
77988-07-9Relevant articles and documents
Formation of trioxadamantane type aglucones of 3-methoxy secologanin derivatives
Krajsovszky, Gabor,Kocsis, Akos,Szabo, Laszlo Ferenc,Podanyi, Benjamin
, p. 11659 - 11668 (1997)
Acidic transformation of some 3,4-dihydro-3-substituted secologanin derivatives produced trioxadamantane type compounds. The formation of the bridged tricyclic products from monocyclic educts is interpreted as multistep hydrolysis and transacetalation accompanied by deglucosylation.
SELECTIVE TRANSFORMATIONS OF SECOLOGANIN: DIHYDROXYLATION
Purdy, John Richard,Hamilton, Raymond G.,Akhter, Lalarukh,McLean, Stewart
, p. 210 - 214 (2007/10/02)
Sweroside tetraacetate ( 2b ) has been converted in high yield by osmylation to the epimeric glycols 3 and 4 ( R=H ) which have been separated.This reaction proceeds with high chemoselectivity for reaction at the vinyl side chain but with low stereoselectivity, leading to a small excess of the 3-R isomer.Secologanin derivatives appear to show a much lower chemoselectivity in this reaction, but the stereoselectivity is considerably higher, and opposite to that in the sweroside example.Conditions have been found for oxidizing the dimethylacetal 5b of secologanin tetraacetate in useful yields to the epimeric glycols 6 and 7 ( R=H ); in this reaction a large excess of the 3-S isomer is formed.The reasons for these differences in selectivity appear to be related to differences between the two series in conformational preference.