77495-66-0

Basic information

• Product Name: (R)-(+)-1,2-EPOXYOCTANE
• Synonyms: (R)-(+)-1,2-EPOXYOCTANE;(R)-1,2-EPOXYOCTANE;(R)-(+)-1-Octene oxide;(R)-(+)-1,2-Epoxyoctane, GC 95%;Bupirimate PESTANAL;(2R)-2-HEXYL-OXIRANE;(R)-(+)-1-Octene oxide, (R)-(+)-2-Hexyloxirane;(2R)-1,2-Epoxyoctane
• CAS NO: 77495-66-0
• Molecular Formula: C₈H₁₆O
• Molecular Weight: 128.21
• Mol File: 77495-66-0.mol
• Article Data: 66

Chemical Properties

• Boiling Point: 60-62 °C15 mm Hg(lit.)
• Flash Point: 99 °F
• Appearance: /
• Density: 0.839 g/mL at 25 °C(lit.)
• Refractive Index: n20/D 1.420
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (R)-(+)-1,2-EPOXYOCTANE(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(+)-1,2-EPOXYOCTANE(77495-66-0)
• EPA Substance Registry System: (R)-(+)-1,2-EPOXYOCTANE(77495-66-0)

Safety Data

• Hazard Codes: Xi
• Statements: 10-36/37/38
• Safety Statements: 26-36/37/39
• RIDADR: UN 3271 3/PG 3
• WGK Germany: 3
• F: 9-21
• Hazardous Substances Data: 77495-66-0(Hazardous Substances Data)

Usage

General Description

(R)-(+)-1,2-EPOXYOCTANE is a chemical compound with the molecular formula C8H16O. It is an epoxide, which means it contains a three-membered ring consisting of one oxygen atom and two carbon atoms. (R)-(+)-1,2-EPOXYOCTANE is primarily used as a cross-linker or curing agent in the production of polymers and resins, particularly in the manufacturing of adhesives, coatings, and sealants. It is also commonly used in the synthesis of pharmaceuticals and agrochemicals. Additionally, (R)-(+)-1,2-EPOXYOCTANE is utilized as a reagent in organic chemistry reactions, where its high reactivity and stereospecificity make it useful for various synthetic applications. The (R)-(+)- enantiomer of 1,2-EPOXYOCTANE is considered to have specific properties and applications, making it an important molecule in the field of organic chemistry and materials science.

Upstream product

• 20542-98-7 (R)-1-dimethylamino-octan-2-ol 
• 111-66-0 oct-1-ene 
• 145107-40-0 (R)-1-tert-Butylsulfanyl-octan-2-ol 
• 377778-48-8 (R)-4-Hexyl-[1,3,2]dioxathiolane 2,2-dioxide 
• 2984-50-1 1,2-Epoxyoctane 
• 685128-68-1 (S)-2-chlorooctanal 
• 124190-50-7 (R)-1-chloro-2-octanol 
• 63988-10-3 1-chloro-2-octanone 
• 111-25-1 1-bromo-hexane 
• 124-13-0 Octanal 
• 1117-86-8 (R)-1,2-octanediol 
• 145107-43-3 Chloro-acetic acid 1-tert-butylsulfanylmethyl-heptyl ester 
• 143724-83-8 1-tert-Butylsulfanyl-octan-2-ol 
• 773837-37-9 sodium cyanide 

Downstream Products

• 6169-06-8 (S)-2-Octanol 
• 218904-33-7 (R)-3-[1-(4'-Heptyl-biphenyl-4-yl)-meth-(E)-ylidene]-5-hexyl-dihydro-furan-2-one 
• 218904-15-5 (R)-3-(4'-Heptyl-biphenyl-4-ylmethyl)-5-hexyl-3-phenylsulfanyl-dihydro-furan-2-one 
• 218904-04-2 (R)-3-(4'-Heptyl-biphenyl-4-ylmethyl)-5-hexyl-dihydro-furan-2-one 
• 119259-50-6 (S)-2-fluoro-1-p-toluenesulfonyloxyoctane 
• 1142934-13-1 (R)-1-(benzyloxy)tridecan-7-ol 
• 1093117-20-4 (S)-1-(4-methoxybenzyloxy)dodecan-6-ol 
• 1117-86-8 (S)-octane-1,2-diol 
• 1117-86-8 (R)-1,2-octanediol 
• 1401564-82-6 C₁₄H₂₃N 
• 179396-72-6 C₁₄H₂₂O 
• 403996-34-9 (2S,4R)-4-acetoxy-2-(4-hydroxyphenyl)decanenitrile 
• 403996-36-1 (2R,4R)-4-acetoxy-2-(4-hydroxyphenyl)decanenitrile 
• 403996-31-6 (2S,4R)-4-acetoxy-2-(4-methoxyphenyl)decanenitrile 

Relevant articles and documents

Are Highly Stable Covalent Organic Frameworks the Key to Universal Chiral Stationary Phases for Liquid and Gas Chromatographic Separations?

High-performance liquid chromatography (HPLC) and gas chromatography (GC) over chiral stationary phases (CSPs) represent the most popular and highly applicable technology in the field of chiral separation, but there are currently no CSPs that can be used for both liquid and gas chromatography simultaneously. We demonstrate here that two olefin-linked covalent organic frameworks (COFs) featuring chiral crown ether groups can be general CSPs for extensive separation not only in GC but also in normal-phase and reversed-phase HPLC. Both COFs have the same 2D layered porous structure but channels of different sizes and display high stability under different chemical environments including water, organic solvents, acids, and bases. Chiral crown ethers are periodically aligned within the COF channels, allowing for enantioselective recognition of guest molecules through intermolecular interactions. The COF-packed HPLC and GC columns show excellent complementarity and each affords high resolution, selectivity, and durability for the separation of a wide range of racemic compounds, including amino acids, esters, lactones, amides, alcohols, aldehydes, ketones, and drugs. The resolution performances are comparable to and the versatility is superior to those of the most widely used commercial chiral columns, showing promises for practical applications. This work thus advances COFs with high stability as potential universal CSPs for chromatography that are otherwise hard or impossible to produce.

Asymmetric Epoxidation of Olefins Catalyzed by Substituted Aminobenzimidazole Manganese Complexes Derived from L-Proline

A family of manganese complexes [Mn(Rpeb)(OTf)2] (peb=1-(1-ethyl-1H-benzo[d]imidazol-2-yl)-N-((1-((1-ethyl-1H-benzo[d]imidazol-2-yl)methyl) pyrrolidin-2-yl)methyl)-N-methylmethanamine)) derived from L-proline has been synthesized and characterized, where R refers to the group at the diamine backbone. X-ray crystallographic analyses indicate that all the manganese complexes [Mn(Rpeb)(OTf)2] exhibit cis-α topology. These types of complexes are shown to catalyze the asymmetric epoxidation of olefins employing H2O2 as a terminal oxidant with up to 96% ee. Obviously, the R group of the diamine backbone can influence the catalytic activity and enantioselectivity in the asymmetric epoxidation of olefins. In particular, Mn(i-Prpeb)(OTf)2 bearing an isopropyl arm, cannot catalyze the epoxidation reaction with H2O2 as the oxidant. However, when PhI(OAc)2 is used as the oxidant instead, all the manganese complexes including Mn(i-Prpeb)(OTf)2 can promote the epoxidation reactions efficiently. Taken together, these results indicate that isopropyl substitution on the Rpeb ligand inhibits the formation of active Mn(V)-oxo species in the H2O2/carboxylic acid system via an acid-assisted pathway.

Chiral salen Mn (III) immobilized on ZnPS-PVPA through alkoxyl-triazole for superior performance catalyst in asymmetric epoxidation of unfunctionalized olefins

Chiral salen Mn (III) catalysts anchored onto ZnPS-PVPA via click chemistry are prepared and applied in asymmetric epoxidations of unfunctionalized olefins. Superior catalytic performances (conv%, up to >99; ee%, up to >99) are achieved in the epoxidations of α-methylstyrene, styrene, indene and 1-octene. According to 6-cyano-2,2-dimethylchromene and 6-nitro-2,2-dimethylchromene, configuration of epoxides are reversed. And then the catalysts are selective in not only oxidative systems, but also substrates. Moreover, superior reusability (yield, 82%; ee, 86%) after recycling for nine times could also be obtained, which provide the potential application in industry.