77420-44-1

Basic information

• Product Name: Benzamide, N,N-diethyl-2-formyl-
• CAS NO: 77420-44-1
• Molecular Formula: C12H15NO2
• Molecular Weight: 205.257
• Mol File: 77420-44-1.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: Benzamide, N,N-diethyl-2-formyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, N,N-diethyl-2-formyl-(77420-44-1)
• EPA Substance Registry System: Benzamide, N,N-diethyl-2-formyl-(77420-44-1)

Safety Data

• Hazardous Substances Data: 77420-44-1(Hazardous Substances Data)

Upstream product

• 79422-68-7 Phthalsaeure-mono-(N,N-diethylamid)-chlorid 
• 127787-11-5 N-(Bis-trimethylsilanyl-methyl)-N',N'-diethyl-N-methyl-phthalamide 
• 117886-88-1 2-formyl benzoyl chloride 
• 109-89-7 diethylamine 
• 119-67-5 o-carboxybenzaldehyde 
• 1696-17-9 N,N-diethylbenzamide 
• 68-12-2 N,N-dimethyl-formamide 
• 109-94-4 formic acid ethyl ester 
• 76041-86-6 2-bromo-N,N-diethylbenzamide 
• 6940-49-4 3-Bromophthalide 
• 87-41-2 2-benzofuran-1(3H)-one 
• 4166-52-3 2-(diethylcarbamoyl)benzoic acid 
• 127787-04-6 N-(Bis-trimethylsilanyl-methyl)-N-methyl-benzamide 
• 88-10-8 N,N-diethylcarbamyl chloride 

Downstream Products

• 1696-17-9 N,N-diethylbenzamide 
• 61260-15-9 dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate 
• 27613-27-0 3-oxo-1,3-dihydroisobenzofuran-1-carbonitrile 
• 103258-32-8 N,N-diethyl-2-(bromomethyl)benzamide 
• 220208-86-6 (S)-N,N-diethyl-o-(2,2-dimethyl-1-hydroxy-3-butenyl)benzamide 
• 220208-81-1 N,N-diethyl-o-(3-methyl-2-butenyloxymethyl)benzamide 
• 220208-73-1 N,N-diethyl-o-allyloxymethylbenzamide 
• 233589-52-1 N,N-diethyl-o-hydroxy(deuteriomethyl)benzamide 
• 103258-38-4 N,N-diethyl-2-(hydroxymethyl)benzamide 
• 344556-62-3 2-(Buten(1')-on(3')yl)-N,N-diethyl-benzoesaeureamid 
• 113232-67-0 2-(Cyano-trimethylsilanyloxy-methyl)-N,N-diethyl-benzamide 
• 77420-45-2 (E)-NN-diethyl-2-<2-(4-oxo-4H-1-benzopyran-2-yl)vinyl>benzamide 
• 77420-47-4 NN-diethyl-2-<2-(4-oxo-4H-1-benzopyran-2-yl)ethyl>benzamide 

Relevant articles and documents

Development of a Rhodium(II)-Catalyzed Chemoselective C(sp3)-H Oxygenation

We report the first example of RhII-catalyzed chemoselective double C(sp3)-H oxygenation, which can directly transform various toluene derivatives into highly valuable aromatic aldehydes with great chemoselectivity and practicality. The critical combination of catalyst Rh(OAc)2, oxidant Selectfluor, and solvents of TFA/TFAA promises the successful delivery of the oxidation with satisfactory yields. A possible mechanism involving a unique carbene-Rh complex is proposed, and has been supported by both experiments and theoretical calculations.

The investigation of nucleophilic reactions of 3 -bromo/chloro phthalide with amines

The reaction of 3-bromo/chloro phthalide 1a/b with secondary amines in polar solvents gives the corresponding amides of 2-formylbenzoic acid, while in nonpolar solvents gives 3-aminophthalides. The reaction of 1a/b with aromatic primary amines gives 3-arylaminophthalides, while with aliphatic primary amines 3-hydroxyphthalimidines are obtained.

A regioselective synthesis of dimethyl phthalide-3-phosphonates

Dimethyl phthalide-3-phosphonates having various substituents on the benzene ring were regioselectively synthesized by the reaction of N,N-diethyl-2-formylbenzamides with tert-butyldimethylsilyl dimethyl phosphite followed by treatment with methanesulfonic acid. N,N-Diethyl-2-formylbenzamides were regioselectively prepared by ortho lithiation-formylation of the corresponding benzamides.