77172-72-6

Basic information

• Product Name: 3,4,5,6-Tetrabromophenolsulfonephthalein
• Synonyms: 3,4,5,6-Tetrabromophenolsulfonephthalein;4,5,6,7-Tetrabromo-3,3-bis(p-hydroxyphenyl)-3H-2,1-benzoxathiole 1,1-dioxide;4,5,6,7-Tetrabromophenolsulfonephthalein;4,5,6,7-Tetrabromophenolsulfophthalein;Tetrabromosulfonephthalein;Aids044105;Aids-044105;Nsc624919
• CAS NO: 77172-72-6
• Molecular Formula: C₁₉H₁₀Br₄O₅S
• Molecular Weight: 670.97
• Product Categories: Stains and Dyes;Stains&Dyes, A to;T-U-V
• Mol File: 77172-72-6.mol
• Article Data: 2

Chemical Properties

• Melting Point: 270-271 °C
• Boiling Point: 696.1 °C at 760 mmHg
• Flash Point: 374.8 °C
• Appearance: /
• Density: 2.199 g/cm³
• Vapor Pressure: 5.03E-20mmHg at 25°C
• Refractive Index: 1.743
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 7.88±0.50(Predicted)
• CAS DataBase Reference: 3,4,5,6-Tetrabromophenolsulfonephthalein(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4,5,6-Tetrabromophenolsulfonephthalein(77172-72-6)
• EPA Substance Registry System: 3,4,5,6-Tetrabromophenolsulfonephthalein(77172-72-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26
• WGK Germany: 3
• Hazardous Substances Data: 77172-72-6(Hazardous Substances Data)

Usage

General Description

3,4,5,6-Tetrabromophenolsulfonephthalein is a chemical compound that is commonly used as a pH indicator in laboratories. It has a vibrant red color in acidic conditions and transitions to yellow in basic conditions, making it a useful tool for determining the acidity or alkalinity of a solution. 3,4,5,6-Tetrabromophenolsulfonephthalein is also known for its stability and resistance to environmental factors, making it suitable for long-term use. Additionally, it is important to handle 3,4,5,6-Tetrabromophenolsulfonephthalein with care as it may cause skin and eye irritation upon contact, and it can be harmful if ingested or inhaled. Overall, 3,4,5,6-Tetrabromophenolsulfonephthalein is a valuable chemical compound for its role as a pH indicator, but it should be handled and used with caution due to its potential health hazards.

InChI:InChI=1/C19H10Br4O5S/c20-14-13-18(17(23)16(22)15(14)21)29(26,27)28-19(13,9-1-5-11(24)6-2-9)10-3-7-12(25)8-4-10/h1-8,24-25H

Synthetic route

phenol (108-95-2) + <3.4.5.6-tetrabromo-2-sulfo-benzoic acid >-endo anhydride → 4,5,6,7-tetrabromo-3,3-bis-(4-hydroxy-phenyl)-3H-benz[c][1,2]oxathiol-1,1-dioxide (77172-72-6)

Conditions	Yield
With tin(IV) chloride at 130 - 140℃;

Upstream product

• 108-95-2 phenol 

Relevant articles and documents

Test-strip containing merocyanine and nitro or nitroso substituted polyhalogenated phenol-sulfonephthaleins as protein indicators

The present invention provides an analytical test strip for the detection of protein in a biological sample including a novel combination of protein error indicators. The invention includes, in combination, a partially halogenated phenolsulfonephthalein protein error indicator having nitro or nitroso substituent groups in the B and/or C rings and a merocyanine protein error indicator.