76843-23-7 Usage
Cytotoxicity
IC50 (μg/mL): 0.77 (5637), 1.73 (A-427),0.34 (MCF-7) (Mothana et al. 2009)IC50 (μg/mL): 2.3 (Hep-2), 1.7 (A549), 1.9(SK-OV-3), 1.6 (SK-MEL-2) 0.8 (XF498)(Wang et al. 2007), IC50 (μg/mL): 23(P-388) (Zhao et al. 2011)IC50 (μg/mL): 2.3 (A549), 1.7 (SK-OV-3),1.9 (SK-MEL-2), 1.96 (XF498), 0.8(HCT15) (Zhang et al. 2013)
Check Digit Verification of cas no
The CAS Registry Mumber 76843-23-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,8,4 and 3 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 76843-23:
(7*7)+(6*6)+(5*8)+(4*4)+(3*3)+(2*2)+(1*3)=157
157 % 10 = 7
So 76843-23-7 is a valid CAS Registry Number.
76843-23-7Relevant articles and documents
New application of tanshinone IIA derivatives as MAGL (monoacylglycerol lipase) inhibitor
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Paragraph 0012; 0029, (2017/09/12)
The invention relates to the field of pharmaceutical chemistry, specifically to medical application of tanshinone IIA derivatives (I) and (II). Pharmacological experiments show that the compound has strong monoacylglycerol lipase inhibitory activity and good analgesic activity. The compound is expected to be used for developing a novel analgesic drug based on the clinic use of a monoacylglycerol lipase inhibitor.
