76792-94-4

Basic information

• Product Name: 3-Hydroxy-4',5,7-trimethoxyflavane
• Synonyms: 3-Hydroxy-4',5,7-trimethoxyflavane;3-Hydroxy-4',5,7-triMethoxyflavanone;(2R,3R)-2,3-Dihydro-3-hydroxy-5,7-dimethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one;5,7,4'-Tri-O-MethylaroMadendrin;3-Hydroxy-5,7-diMethoxy-2-(4-Methoxyphenyl)chroMan-4-one
• CAS NO: 76792-94-4
• Molecular Formula: C₁₈H₁₈O₆
• Molecular Weight: 330.33192
• Mol File: 76792-94-4.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 547.772 °C at 760 mmHg
• Flash Point: 200.688 °C
• Appearance: /
• Density: 1.285 g/cm³
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-Hydroxy-4',5,7-trimethoxyflavane(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Hydroxy-4',5,7-trimethoxyflavane(76792-94-4)
• EPA Substance Registry System: 3-Hydroxy-4',5,7-trimethoxyflavane(76792-94-4)

Safety Data

• Hazardous Substances Data: 76792-94-4(Hazardous Substances Data)

Usage

General Description

3-Hydroxy-4',5,7-trimethoxyflavane is a chemical compound belonging to the flavonoid class. It is a naturally occurring polyphenolic compound found in various plants and fruits. The compound has been studied for its potential antioxidant, anti-inflammatory, and anti-cancer properties. It is also known to have neuroprotective effects and may be beneficial for cardiovascular health. Its chemical structure consists of a flavane backbone with hydroxyl and methoxy groups attached at specific positions, which contribute to its biological activities. Overall, 3-Hydroxy-4',5,7-trimethoxyflavane holds promise as a natural compound with potential health benefits, and further research is needed to fully understand its therapeutic potential.

Upstream product

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Downstream Products

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Relevant articles and documents

Stereoselective synthesis of flavonoids. Part 4. Trans- and cis-dihydroflavonols

Epoxidation of a series of poly-oxygenated chalcones with H2O2 in the presence of poly-α-aminoacids yielded chiral aromatic oxygenated oxiranes in moderate to high optical yields. Lewis acid-catalysed phenylmethanethiol ringopening o

Heterocycles. XXII. Stereoselective Synthesis of (+)-Aromadendrin Trimethyl Ether and Its Enantiomer, and Their Reduction

Two enantiomeric chalcone epoxides 2a and 2b are synthesized under phase-transfer conditions using 1-benzylquinidinium chloride and 1-benzylquininium chloride as catalysts, respectively.Stereoselective cyclisation of 2a and 2b, followed by methylation and

Some Novel Photochemical and Related Aryl Couplings and Migrations in Flavonoid Synthesis

2'-Methoxymethoxy-4,4',6'-trimethoxychalcone epoxide couples at the β-position with 3,5-dimethoxyphenol under photolytic conditions to form isomeric 1,3,3-triaryl-2-hydroxypropiophenones.These propiophenones are subject to photo-induced α-ketol rearrangements yielding isomeric 1-hydroxypropan-2-ones.Together these serve as useful synthetic intermediates for 4-arylflavan-3-ones and novel 2-hydroxy-2-arylbenzylbenzofuran-3(2H)-ones and 4-aryl-3-hydroxy-3,4-cis-dihydrocoumarins.The same epoxide reacts ionically under ambient conditions with 2,4,6-trihydroxybenzoic acid to afford a 3-O-benzoylpropiophenone intermediate, which provides novel access to isoflavones in high overall yield.Analogous coupling of phloroglucinol to epoxycinnamates gives diastereoisomeric 3,3-diaryl-2-hydroxypropionates which serve as precursors for 3,4-trans- and 3,4-cis-4-aryl-3-hydroxydihydrocoumarins and thence for 3-aryl- and 3-hydroxycoumarins.