761-88-6Relevant articles and documents
SUBSTITUTED PYRIMIDINES
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Page/Page column 87, (2013/04/10)
Disclosed are substituted pyrimidines useful as HIF prolyl hydroxylase inhibitors to treat anemia and like conditions.
A modified approach to C-14-labeled 2-(3,4-difluorophenoxy)-5- fluoronicotinic acid and other halogen-substituted analogs
Zhang, Yinsheng,Jian, Zhigang,Stolle, Wayne T.
experimental part, p. 382 - 386 (2012/06/01)
A modified approach to a carbon-14-labeled pyridine ring system was developed based on the electrocyclic ring-closure of 1,4,4-trisubstituted butadiene. The new method was applied to prepare 2-(3,4-difluorophenoxy)-5- fluoro-[2-14C] nicotinic a
Extremely simple route to β-fluoro vinamidinium salts: A novel reaction of (polyfluoro-1-propenyl)trimethylammonium iodides with primary or secondary amines
Yamanaka,Yamashita,Ishihara
, p. 357 - 360 (2007/10/02)
(2,3,3-Trifluoro-1-propenyl)trimethylammonium iodide readily underwent demethylation-allylic substitution followed by N-N exchange reaction at ambient temperature or at 70°C by the action of various secondary amines or several primary amines to give the c