75590-33-9

Basic information

• Product Name: Kaerophyllin
• Synonyms: Kaerophyllin;(-)-Kaerophylin;Chaerophyllin
• CAS NO: 75590-33-9
• Molecular Formula: C₂₁H₂₀O₆
• Molecular Weight: 368.3799
• Mol File: 75590-33-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 576.3°C at 760 mmHg
• Flash Point: 253.5°C
• Appearance: /
• Density: 1.308g/cm³
• Vapor Pressure: 2.78E-13mmHg at 25°C
• Refractive Index: 1.624
• CAS DataBase Reference: Kaerophyllin(CAS DataBase Reference)
• NIST Chemistry Reference: Kaerophyllin(75590-33-9)
• EPA Substance Registry System: Kaerophyllin(75590-33-9)

Safety Data

• Hazardous Substances Data: 75590-33-9(Hazardous Substances Data)

Usage

General Description

Kaerophyllin is a medication that contains the active ingredients theophylline and ephedrine. Theophylline is a bronchodilator that relaxes muscles in the airways, improving breathing. It is used to treat conditions such as asthma, bronchitis, and emphysema. Ephedrine is a decongestant and bronchodilator that works by reducing swelling and constricting blood vessels in the nasal passages, improving breathing. Kaerophyllin is commonly prescribed to help manage symptoms of respiratory conditions and improve lung function. However, it is important to use this medication as directed and consult a doctor before use, as it may have potential side effects and interactions with other medications.

InChI:InChI=1/C21H20O6/c1-23-17-5-3-14(9-19(17)24-2)8-16-15(11-25-21(16)22)7-13-4-6-18-20(10-13)27-12-26-18/h3-6,8-10,15H,7,11-12H2,1-2H3/b16-8+/t15-/m0/s1

Upstream product

• 126313-83-5 3,4-trans-2α-piperonylmethyl-3-hydroxymethyl-4-veratryl-3-buten-1-ol 
• 145274-62-0 Isoguamarol 
• 126574-52-5 isokaerophyllin 
• 186581-53-3 diazomethane 
• 145274-61-9 Guamarol 

Downstream Products

• 126452-80-0 2α-veratrylmethyl-3α-piperonylmethyl-γ-butyrolactone 
• 40456-51-7 bursehernin 
• 126574-52-5 isokaerophyllin 
• 126313-83-5 3,4-trans-2α-piperonylmethyl-3-hydroxymethyl-4-veratryl-3-buten-1-ol 
• 126313-81-3 Acetic acid (R)-3-acetoxymethyl-4-benzo[1,3]dioxol-5-yl-2-[1-(3,4-dimethoxy-phenyl)-meth-(Z)-ylidene]-butyl ester 
• 126313-82-4 Acetic acid (R)-3-acetoxymethyl-4-benzo[1,3]dioxol-5-yl-2-[1-(3,4-dimethoxy-phenyl)-meth-(E)-ylidene]-butyl ester 
• 126313-80-2 3,4-cis-2α-piperonylmethyl-3-hydroxymethyl-4-veratryl-3-buten-1-ol 

Relevant articles and documents

Synthesis, anti-virus and anti-tumour activities of dibenzylbutyrolactone lignans and their analogues

An efficient synthesis of dibenzylbutyrolactone lignans and their analogues has been developed. Based on a Stobbe condensation of piperonal or veratraldehyde with diethylsuccinate and alkylation with 3,4- methylenedioxybenzyl bromide to give the skeleton

Isokaerophyllin, a butyrolactone from Bupleurum salicifolium

From the leaves of Bupleurum salicifolium two benzylidene-benzyl-γ-butyrolactone-type lignans were isolated. One was identified as kaerophyllin, the other as its cis-isomer, hitherto unreported. The latter was characterized as 2(3,4-dimethoxy)-benzylidene