7417-68-7

Basic information

• Product Name: 2-methoxy-6-methylbenzene-1,4-diol
• CAS NO: 7417-68-7
• Molecular Formula: C₈H₁₀O₃
• Molecular Weight: 154.1632
• Mol File: 7417-68-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 321.3°C at 760 mmHg
• Flash Point: 148.1°C
• Density: 1.217g/cm³
• Vapor Pressure: 0.00016mmHg at 25°C
• Refractive Index: 1.569
• CAS DataBase Reference: 2-methoxy-6-methylbenzene-1,4-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methoxy-6-methylbenzene-1,4-diol(7417-68-7)
• EPA Substance Registry System: 2-methoxy-6-methylbenzene-1,4-diol(7417-68-7)

Safety Data

• Hazardous Substances Data: 7417-68-7(Hazardous Substances Data)

Upstream product

• 765-47-9 1,2-dimethylcyclopentene 
• 72312-08-4 2-methyl-4,4,5-trimethoxycyclohexa-2,5-dienone 
• 7782-99-2 sulphurous acid 
• 614-13-1 2-methoxy-5-methyl-1,4-benzoquinone 
• 7721-62-2 4,5-dimethoxy-2-methylbenzaldehyde 
• 4949-20-6 (E)-2,4-pentadien-1-ol 
• 1195-09-1 5-methyl-2-methoxyphenol 
• 29865-97-2 2,5-dihydroxy-4-methoxy-benzaldehyde 
• 64-19-7 acetic acid 

Downstream Products

• 490-64-2 asaronic acid 
• 97242-31-4 2,5-di(3-acetoxy-5-methoxybenzoyloxy)-4-methoxybenzyl bromide 
• 97242-32-5 5-(3-acetoxy-5-methoxybenzoyloxy)-2-(3-acetoxy-5-methoxyphenyl)-6-methoxybenzofuran 
• 67259-16-9 2-(3-hydroxy-5-methoxyphenyl)-6-methoxy-5-benzofuranol 
• 97265-24-2 2,5-di(3-acetoxy-5-methoxybenzoyloxy)-4-methoxytoluene 
• 100118-34-1 2-methoxy-5-methyl-1,4-benzenediol diacetate 
• 112649-72-6 2,5-bis(2-benzyloxy-4-methoxybenzoyloxy)-4-methoxytoluene 
• 14894-74-7 1,2,4-trimethoxy-5-methylbenzene 
• 614-13-1 2-methoxy-5-methyl-1,4-benzoquinone 
• 112649-75-9 2,5-bis(2-acetoxy-4-methoxybenzoyloxy)-4-methoxybenzyl bromide 
• 112649-74-8 2,5-bis(2-acetoxy-4-methoxybenzoyloxy)-4-methoxytoluene 
• 112649-70-4 2,5-bis(2,4-dimethoxybenzoyloxy)-4-methoxybenzyl bromide 
• 112649-73-7 2,5-bis(2-hydroxy-4-methoxybenzoyloxy)-4-methoxytoluene 
• 90664-32-7 5-Hydroxy-2-(2-hydroxy-4-methoxyphenyl)-6-methoxybenzofuran 

Relevant articles and documents

Dual behavior of masked o-benzoquinones in intramolecular Diels-Alder reactions. Expedient synthesis of highly functionalized cis-decalins from 2-methoxyphenols

The potential dual behavior as dienes and dienophiles of the diene moieties of masked o-benzoquinones (MOBs) 10a-e-12a-e, generated upon oxidation of 2-methoxyphenols 1-3 with BTIB in the presence of appropriate dienols, in their intramolecular Diels-Alde

A synthesis of gymnomitrol

Condensation of 1,2 - dimethylcyclopentene 10 with 2 - methyl - 4,4, 5 - trimethoxycyclohexa - 2,5 -dienone 7 in methylene chloride - nitromethane with added stannic chloride gave a mixture of the two diastereo-meric bicyclo[3.2.1]octanes 13 and 14 by ionic [4+2]cycloaddition. After selective reduction of the saturated carbonyl group with sodium borohydride, and hydrogenation of the double bond the two epimers 18 and 20 (ratio 3.3:1) were separable by chromatography. Protection of the hydroxy group in 18 with dihydropyran and, reduction of the α-methoxyketone 19 with calcium in liquid ammonia gave ketone 21. Gymnomitrol 1 was then prepared by Wittig olefination followed by deprotection of the hydroxy group.