73731-86-9

Basic information

• Product Name: Broussonin B
• Synonyms: Broussonin B;4-[3-(4-Hydroxyphenyl)propyl]-3-methoxyphenol
• CAS NO: 73731-86-9
• Molecular Formula: C₁₆H₁₈O₃
• Molecular Weight: 258.31232
• Mol File: 73731-86-9.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Broussonin B(CAS DataBase Reference)
• NIST Chemistry Reference: Broussonin B(73731-86-9)
• EPA Substance Registry System: Broussonin B(73731-86-9)

Safety Data

• Hazardous Substances Data: 73731-86-9(Hazardous Substances Data)

Usage

General Description

Broussonin B is a chemical compound isolated from the leaves of the plant Broussonetia kazinoki. It is a flavonoid with potential therapeutic properties. Studies have shown that Broussonin B possesses anti-inflammatory, antioxidant, and anti-cancer activities. It has been found to inhibit the growth of various cancer cell lines, including lung, liver, and breast cancer cells. Broussonin B also exhibits protective effects against oxidative stress-induced cell damage. Its anti-inflammatory properties make it a potential candidate for the treatment of inflammatory diseases. Overall, Broussonin B is a promising compound with diverse biological activities and potential applications in medicine.

Upstream product

• 1286280-47-4 4-(benzyloxy)-2-methoxy-1-vinylbenzene 
• 58026-14-5 4-(benzyloxy)-2-methoxybenzaldehyde 
• 18278-34-7 4-hydroxy-2-methoxybenzaldehyde 

Downstream Products

• 1372551-34-2 4-hydroxy-4-(3-(4-hydroxyphenyl)propyl)-3-methoxycyclohexa-2,5-dienone 

Relevant articles and documents

Concise synthesis of broussonone A

A concise and expeditious approach to the total synthesis of broussonone A, a p-quinol natural compound, has been developed. The key features of the synthesis include the Grubbs II catalyst mediated cross metathesis of two aromatic subunits, and a chemoselective oxidative dearomatizationin the presence of two phenol moieties. Especially, optimization associated with the CM reaction of ortho-alkoxystyrenes was also studied, which are known to be ineffective for Ru-catalyzed metathesis reactions under conventional reaction conditions because ortho-alkoxy group could coordinate to the ruthenium center, resulting in the potential complication of catalyst inhibition.