737000-84-9

Basic information

• Product Name: (S)-(+)-1-INDANYL ISOTHIOCYANATE
• Synonyms: (S)-(+)-1-INDANYL ISOTHIOCYANATE;(S)-1-isothiocyanato-2,3-dihydro-1H-indene
• CAS NO: 737000-84-9
• Molecular Formula: C10H9NS
• Molecular Weight: 175.25
• Mol File: 737000-84-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 108-113°C 0,1mm
• Flash Point: 108-113°C/0.1mm
• Appearance: /
• Density: 1,146 g/cm3
• Refractive Index: 1.6130
• Sensitive: Moisture Sensitive
• CAS DataBase Reference: (S)-(+)-1-INDANYL ISOTHIOCYANATE(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(+)-1-INDANYL ISOTHIOCYANATE(737000-84-9)
• EPA Substance Registry System: (S)-(+)-1-INDANYL ISOTHIOCYANATE(737000-84-9)

Safety Data

• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39
• RIDADR: 2810
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 737000-84-9(Hazardous Substances Data)

Usage

Description

(S)-(+)-1-Indanyl isothiocyanate is a chemical compound belonging to the isothiocyanate family. It is a chiral molecule, with the (+)-enantiomer being the active form. (S)-(+)-1-Indanyl isothiocyanate is recognized for its potential pharmaceutical and medicinal applications, particularly due to its demonstrated anticancer and anti-inflammatory properties in preclinical studies. Additionally, it is being explored for its possible use as a flavoring and fragrance agent.

Uses

Used in Pharmaceutical and Medicinal Applications:
(S)-(+)-1-Indanyl isothiocyanate is used as a pharmaceutical agent for its potential anticancer properties. Preclinical studies have shown that it exhibits promising effects against various types of cancer, making it a candidate for further research and development in the field of oncology.
(S)-(+)-1-Indanyl isothiocyanate is also used as an anti-inflammatory agent due to its demonstrated ability to reduce inflammation in preclinical studies. This property makes it a potential candidate for the development of new treatments for inflammatory diseases.
Used in Flavoring and Fragrance Industry:
(S)-(+)-1-Indanyl isothiocyanate is used as a flavoring agent in the food and beverage industry. Its unique chemical structure contributes to the development of novel flavors, enhancing the taste profiles of various products.
(S)-(+)-1-Indanyl isothiocyanate is used as a fragrance agent in the cosmetics and perfumery industry. Its distinct chemical properties allow for the creation of new and innovative scents, adding value to fragrance formulations.

Upstream product

• 60212-02-4 trans-2-iodo-1-isothiocyanato-indan 
• 463-56-9 thiocyanic acid 
• 95-13-6 1-indene 
• 463-71-8 thiophosgene 
• 34698-41-4 2,3-dihydro-1H-inden-1-amine 
• 2290-65-5 trimethylsilyl isothiocyanate 
• 496-11-7 INDANE 

Relevant articles and documents

Electrochemical Benzylic C(sp3)-H Isothiocyanation

Selective C(sp3)-H isothiocyanation represents a significant strategy for the synthesis of isothiocyanate derivatives. We report herein an electrochemical benzylic isothiocyanation in a highly chemo- and site-selective manner under external oxidant-free conditions. The high chemoselectivity is attributed to the facile in situ isomerization of benzylic thiocyanates to isothiocyanates. Notably, the method exhibits high functional group compatibility and is suitable for late-stage functionalization of bioactive molecules.

INDANYL-AND TETRAHYDRONAPHTYL-AMINO-THIOUREA COMPOUNDS FOR COMBATING ANIMAL PESTS

Indanyl- and Tetrahydronaphtyl-amino-thiourea compounds for combating animal pests The present invention relates to Indanyl- and Tetrahydronaphtyl-amino-thiourea compounds of formula I wherein the variables R1 to R4 are as in the des