73452-24-1

Basic information

• Product Name: N-(bis-p-methoxyphenylphosphinoyl)-O-methylsulphonylhydroxylamine
• CAS NO: 73452-24-1
• Molecular Weight: 371.351
• Mol File: 73452-24-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(bis-p-methoxyphenylphosphinoyl)-O-methylsulphonylhydroxylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(bis-p-methoxyphenylphosphinoyl)-O-methylsulphonylhydroxylamine(73452-24-1)
• EPA Substance Registry System: N-(bis-p-methoxyphenylphosphinoyl)-O-methylsulphonylhydroxylamine(73452-24-1)

Safety Data

• Hazardous Substances Data: 73452-24-1(Hazardous Substances Data)

Upstream product

• 20434-06-4 bis(4-methoxyphenyl)phosphinic acid chloride 
• 73452-54-7 N-(bis-p-methoxyphenylphosphinoyl)hydroxylamine 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 73452-27-4 N',P-bis-p-methoxyphenyl-N-t-butylphosphonic diamide 

Relevant articles and documents

Preparation and Characterisation of N-(Diphenylphosphinoyl)hydroxylamine, and Conversion into O-Sulphonyl Derivatives that undergo Lossen-like Rearrangement

Having previously shown that diphenylphosphinic chloride (1a) forms O-(diphenylphosphinoyl)hydroxylamine (3a) with hydroxylamine, we have now established that N-(diphenylphosphinoyl)hydroxylamine (2a) can be obtained in good yield by reaction of (1a) with O-trimethylsilylhydroxylamine followed by methanolytic removal of the silyl blocking group.The di-p-tolyl (2b) and bis-p-methoxyphenyl (2c) analogues can be prepared in a similar way.N-(Diphenylphosphinoyl)hydroxylamine is acetylated at the O atom with acetic anhydride, and is sulphonylated at O with methanesulphonyl chloride and toluene-p-sulphonyl chloride.The N-(diphenylphosphinoyl)-O-sulphonylhydroxylamines (8) and (12a) undergo rapid and quantitative Lossen-like rearrangement with methanol-sodium methoxide to give methyl N,P-diphenylphosphonamidate (11).Comparable rearrangement are observed with t-butylamine, aniline-triethylamine, and phenol-triethylamine.