732-26-3Relevant articles and documents
Selective Preparations; 27. A Convenient Preparation of 1-Hydroxydibenzofuran from 2-Bromo-4,6-di-t-butylphenol
Tashiro, Masashi,Yoshiya, Haruo,Fukata, Gouki
, p. 495 - 496 (1980)
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Westerberg, D. Eric,Sutherland, Bruce R.,Huffman, John C.,Caulton, Kenneth G.
, p. 1642 - 1643 (1988)
ACTIVITY OF SECONDARY AROMATIC AMINES AS CATALYSTS IN THE REACTION OF STERICALLY HINDERED AROXYL RADICALS WITH HYDROPEROXIDES
Varlamov, V. T.
, p. 482 - 490 (1989)
Secondary aromatic amines AmH catalyze the reaction of the 2,4,6-tri-t-butylphenoxyl radical ArO* with cumyl hydroperoxide ROOH.This effect is closely connected with the antioxidant action of the mixtures of sterically hindered phenols and AmH which have a synergistic effect and which are used in practice.The present work is directed to a study of the dependence of the catalytic activity of AmH on the temperature and on the substituents on the aromatic rings.
Method for synthesizing 2, 4 and 6 -tert-butylphenol
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Paragraph 0032-0082, (2021/11/14)
The invention belongs to the technical field of organic synthesis, and particularly relates to a method for synthesizing 2, 4 and 6 - tri-tert-butylphenol, which comprises the following steps: 1) adding phenol, a catalyst, demineralized water, heating and stirring. 2) To the isobutene, maintain temperature pressure, stirring. 3) Aqueous sodium carbonate aqueous solution, neutralization reaction, washing of the oil phase, separation of the oil phase and the aqueous phase. 4) The oil phase is rectified, and a reaction intermediate product is obtained at the top of the tower, which is used as a reaction material for the next kettle reaction to continue to be alkylated. 2, 4 and 6 -tert-butylphenol crude product is obtained in the tower kettle. 5) The crude product was recrystallized and dried with ethanol as a solvent to give 2, 4, 6 -tert-butylphenol product. The synthesis method provided by the invention is scientific and reasonable in design, adopts micro negative pressure pressure conditions as reaction pressure conditions, effectively avoids the self-polymerization phenomenon of isobutene, is mild and controllable in overall reaction conditions, and is low in reaction temperature, free of byproducts and high in product purity.
Aryl phenol compound as well as synthesis method and application thereof
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Paragraph 0121-0124, (2021/05/12)
The invention discloses a synthesis method of an aryl phenol compound shown as a formula (3). All systems are carried out in an air or nitrogen atmosphere, and visible light is utilized to excite a photosensitizer for catalyzation. In a reaction solvent, ArNR1R2 as shown in a formula (1) and water as shown in a formula (2) are used as reaction raw materials and react under the auxiliary action of acid to obtain the aryl phenol compound as shown in a formula (3). The ArNR1R2 in the formula (1) can be primary amine and tertiary amine, can also be steroid and amino acid derivatives, and can also be drugs or derivatives of propofol, paracetamol, ibuprofen, oxaprozin, indomethacin and the like. The synthesis method has the advantages of cheap and easily available raw materials, simple reaction operation, mild reaction conditions, high reaction yield and good compatibility of substrate functional groups. The fluid reaction not only can realize amplification of basic chemicals, but also can realize amplification of fine chemicals, such as synthesis of drugs propofol and paracetamol. The invention has wide application prospect and use value.