7287-75-4

Basic information

• Product Name: Benzenamine, 2-methoxy-N-(2-methoxyphenyl)-
• CAS NO: 7287-75-4
• Molecular Formula: C14H15NO2
• Molecular Weight: 229.279
• Mol File: 7287-75-4.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: Benzenamine, 2-methoxy-N-(2-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, 2-methoxy-N-(2-methoxyphenyl)-(7287-75-4)
• EPA Substance Registry System: Benzenamine, 2-methoxy-N-(2-methoxyphenyl)-(7287-75-4)

Safety Data

• Hazardous Substances Data: 7287-75-4(Hazardous Substances Data)

Upstream product

• 86759-63-9 ethyl 2-methoxy-N-(2-methoxyphenyl)carbanilate 
• 529-28-2 4-iodoanisol 
• 7429-44-9 2-methoxycyclohexanone 
• 536-90-3 m-Anisidine 
• 766-51-8 2-Chloroanisole 
• 90-04-0 2-methoxy-phenylamine 
• 35601-91-3 ethyl N-(o-methoxyphenyl) carbamate 
• 578-57-4 2-bromoanisole 
• 98-95-3 nitrobenzene 

Downstream Products

• 73405-60-4 1,1-di(o-methoxyphenyl)hydrazine 
• 86759-65-1 ethyl pyruvate 2- 
• 1620194-51-5 C₃₆H₃₂N₄O₄ 
• 73405-58-0 1,1-di(2-methoxyphenyl)urea 

Relevant articles and documents

A green and mild procedure to selective synthesis of diarylamine via domino reaction of aryl halides and arginine catalyzed by magnetic-MOF

Efficient and selective direct synthesis of diarylamines from aryl halides and arginine as a nitrogen-donor reagent is reported. Arginine, which is an oral supplement, acts as a useful nitrogen source donor in the copper-catalyzed reaction. Fe3O4/Cu3(BTC)2, which was easily separated and recycled with a magnet, improved the rate and facilitation of the synthesis of diarylamines selectively. The introduction of a new and available N-source, simple magnetic separation process, normal atmospheric conditions, and excellent yields under mild reaction conditions are other important features of this work.

Formal arylation of NH3 to produce diphenylamines over supported Pd catalysts

In the presence of supported Pd nanoparticle catalysts, e.g., Pd/Al2O3, various diphenylamines could be synthesized through acceptorless formal arylation using NH3 or its surrogates, e.g., urea, as nitrogen sources and cyclohexanones as arylation sources. The observed catalysis was truly heterogeneous, and the catalyst was reusable with retention of its high catalytic performance.

Flexible Steric Bulky Bis(Imino)acenaphthene (BIAN)-Supported N-Heterocyclic Carbene Palladium Precatalysts: Catalytic Application in Buchwald-Hartwig Amination in Air

To achieve efficient palladium-catalyzed cross-coupling reaction under mild reaction conditions with the flexible steric bulk strategy, a series of Pd-PEPPSI (PEPPSI: pyridine-enhanced precatalyst preparation, stabilization, and initiation) complexes C1-C6 were synthesized and characterized, in which unsymmetric flexible steric bulk was introduced on the N-aryl of ancenaphthyl skeleton. These well-defined palladium complexes were found to be excellent precatalysts for Buchwald-Hartwig amination of aryl chlorides with amines in air. The electronic effect of the Pd-PEPPSI complexes and the effect of ancillary pyridine ligands were evaluated, among which complex C3 exhibited the most efficiency. It was demonstrated that the cross-coupling products were obtained in excellent yields in the presence of 0.5-0.1 mol % palladium loading. A wide range of aryl- and heteroaryl chlorides as well as various amines were compatible. The oxidative addition of aryl chlorides is revealed to be the rate-determining step in the catalytic cycle. The catalytic activity can be enhanced by introducing electron-donating groups to the Pd-PEPPSI complexes. This type of Pd-PEPPSI precatalyst showed the most efficiency reported to date for the challenging C-N cross-coupling reactions requiring no anhydrous and inert atmosphere protections, suggesting flexible steric bulk as a promising catalyst design strategy.