726198-18-1 Usage
Description
1-BOC-4-CYANO-4-(2-FLUOROPHENYL)-PIPERIDINE is a chemical compound with the molecular formula C19H23FN2O2. It is a piperidine derivative that is commonly used as an intermediate in the synthesis of various pharmaceuticals and organic compounds. 1-BOC-4-CYANO-4-(2-FLUOROPHENYL)-PIPERIDINE contains a BOC (tert-butoxycarbonyl) protecting group, a cyano group, and a fluorophenyl group, which contribute to its reactivity and biological activity. 1-BOC-4-CYANO-4-(2-FLUOROPHENYL)-PIPERIDINE is often used in organic chemistry research and drug development due to its versatile nature and potential applications in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
1-BOC-4-CYANO-4-(2-FLUOROPHENYL)-PIPERIDINE is used as an intermediate in the synthesis of various pharmaceuticals for its reactivity and biological activity.
Used in Organic Chemistry Research:
1-BOC-4-CYANO-4-(2-FLUOROPHENYL)-PIPERIDINE is used as a versatile compound in organic chemistry research for its potential applications in the development of new organic compounds and pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 726198-18-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,2,6,1,9 and 8 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 726198-18:
(8*7)+(7*2)+(6*6)+(5*1)+(4*9)+(3*8)+(2*1)+(1*8)=181
181 % 10 = 1
So 726198-18-1 is a valid CAS Registry Number.
726198-18-1Relevant articles and documents
Erratum: A new synthesis of spiropyrrolidine-tetralones via an unexpected formal ring-contraction of 4-disubstituted piperidine to 3-disubstituted pyrrolidine (Tetrahedron Letters (2010) 51 (6415-6417))
Bandarage, Upul K.,Davies, Robert J.
, p. 469 - 469 (2011)
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A convenient synthesis of 1′-H-spiro-(indoline-3,4′-piperidine) and its derivatives
Xie, Jian-Shu,Huang, Charles Q.,Fang, Yan-Yan,Zhu, Yun-Fei
, p. 4875 - 4878 (2007/10/03)
A simple synthetic route has been developed to prepare 1′-H- spiro(indoline-3,4′-piperidine) (1d). Dialkylation of 2- fluorophenylacetonitrile with N-(tert-butyloxycarbonyl)-bis(2-chloroethyl)amine (5) gave 6. Deprotection of Boc followed by cyclization resulted 1d in 67% overall yield. Selective Boc or Cbz protection of 1′-N gave 1a or 1b with 90 and 85% yield, respectively. Thus, in a five-step procedure, 1a and 1b were synthesized from commercially available reagents in over 50% overall yield. All 3 compounds (1a, 1b and 1d) can be utilized as templates to synthesize compounds for GPCR targets.