72218-68-9 Usage
Description
2'-Bromo-2'-deoxyuridine, also known as 5-BrdU, is a thymidine analogue that is incorporated into DNA. It is a synthetic nucleoside with a bromine atom at the 2' position, which distinguishes it from natural thymidine. This unique structure allows it to be used as a valuable tool in various biological and medical applications.
Uses
Used in Research Applications:
2'-Bromo-2'-deoxyuridine is used as a research tool for studying cell proliferation and DNA synthesis. Its incorporation into DNA allows researchers to track and measure the rate of cell division, providing valuable insights into cell signaling and other processes that induce cell proliferation.
Used in Biotechnology Industry:
In the biotechnology industry, 2'-Bromo-2'-deoxyuridine is used as a marker for identifying and isolating dividing cells. This is particularly useful in applications such as stem cell research, where the ability to selectively target and study rapidly dividing cells is crucial for understanding their behavior and potential therapeutic applications.
Used in Drug Development:
2'-Bromo-2'-deoxyuridine can also be used in drug development as a means to evaluate the effectiveness of compounds that target DNA synthesis or cell proliferation. By monitoring the incorporation of 5-BrdU into DNA, researchers can assess the impact of potential drugs on cell division and identify promising candidates for further development.
Used in Diagnostic Applications:
In diagnostic applications, 2'-Bromo-2'-deoxyuridine can be employed as a marker for detecting and monitoring diseases characterized by abnormal cell proliferation, such as cancer. By measuring the incorporation of 5-BrdU into DNA, clinicians can gain insights into the rate of tumor growth and the effectiveness of treatments aimed at inhibiting cell division.
Overall, 2'-Bromo-2'-deoxyuridine is a versatile and valuable compound with a wide range of applications in research, biotechnology, drug development, and diagnostics. Its unique properties make it an essential tool for studying cell proliferation and developing new therapies for various diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 72218-68-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,2,1 and 8 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 72218-68:
(7*7)+(6*2)+(5*2)+(4*1)+(3*8)+(2*6)+(1*8)=119
119 % 10 = 9
So 72218-68-9 is a valid CAS Registry Number.
