71989-21-4 Usage
General Description
FMOC-GLN-ONP is a chemical compound consisting of three components: FMOC (fluorenylmethyloxycarbonyl), GLN (glutamine), and ONP (o-nitrophenyl). FMOC-GLN-ONP is commonly used in peptide synthesis and is an important tool in the field of biochemistry and molecular biology. FMOC-GLN-ONP is a derivative of glutamine, a naturally occurring amino acid, and the ONP group is often used to facilitate the removal of FMOC during the peptide synthesis process. FMOC-GLN-ONP is utilized in the protection and deprotection of amino acids in peptide synthesis and plays a crucial role in the production of peptides for biological and pharmaceutical research.
Check Digit Verification of cas no
The CAS Registry Mumber 71989-21-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,9,8 and 9 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 71989-21:
(7*7)+(6*1)+(5*9)+(4*8)+(3*9)+(2*2)+(1*1)=164
164 % 10 = 4
So 71989-21-4 is a valid CAS Registry Number.
71989-21-4Relevant articles and documents
Peptide Synthesis. Part 2. Procedures for Solid-phase Synthesis using Nα-fluorenylmethoxycarbonylamino-acids on Polyamide Supports. Synthesis of Substance P and of Acyl Carrier Protein 65-74 Decapeptide
Atherton, Eric,Logan, Christopher J.,Sheppard, Robert C.
, p. 538 - 546 (2007/10/02)
Use of base-labile Nα-9-fluorenylmethoxycarbonylamino-acids in combination with acid-labile t-butyl or p-alkoxybenzyl side-chain or carboxy-terminal (resin-linkage) protecting groups enables solid-phase peptide synthesis to be carried out under exceptionally mild reaction conditions.The repetitive and vigorous acidic treatments required in conventional synthesis are avoided.High-yield syntheses of a decapeptide and of an undecapeptide amide (Substance P) are described using this new combination of protecting groups on polyamide supports.