71989-14-5 Usage
Description
Fmoc-L-Aspartic acid beta-tert-butyl ester is a synthetic derivative of L-Aspartic acid, a nonessential amino acid that plays a crucial role in the biosynthesis of other amino acids within the human body. The Fmoc (9-fluorenylmethoxycarbonyl) group is a protecting group used in peptide synthesis, while the beta-tert-butyl ester group serves as a temporary protecting group for the carboxylic acid functionality. Fmoc-L-Aspartic acid beta-tert-butyl ester is a white crystalline solid and is soluble in common organic solvents.
Uses
Used in Pharmaceutical Industry:
Fmoc-L-Aspartic acid beta-tert-butyl ester is used as a building block in the synthesis of peptides and proteins for various pharmaceutical applications. The Fmoc group allows for the stepwise assembly of peptide chains, while the beta-tert-butyl ester group protects the carboxylic acid group from unwanted side reactions during the synthesis process.
Used in Research and Development:
Fmoc-L-Aspartic acid beta-tert-butyl ester is used as a research tool in the development of new drugs and therapies. It can be incorporated into peptide-based drug candidates to study their biological activity and potential therapeutic effects.
Used in Biochemical Analysis:
Fmoc-L-Aspartic acid beta-tert-butyl ester can be used in biochemical assays and experiments to investigate the role of L-Aspartic acid in various biological processes, such as enzyme catalysis, metabolic pathways, and protein-protein interactions.
Used in Food and Beverage Industry:
Fmoc-L-Aspartic acid beta-tert-butyl ester can be used as a flavor enhancer in the food and beverage industry. L-Aspartic acid is known to enhance the taste of certain foods and beverages, and its derivatives, such as Fmoc-L-Aspartic acid beta-tert-butyl ester, can be used to achieve similar effects.
Used in Cosmetics Industry:
Fmoc-L-Aspartic acid beta-tert-butyl ester can be used in the development of cosmetic products, such as creams, lotions, and serums, to improve skin health and appearance. L-Aspartic acid is known to play a role in collagen synthesis, and its derivatives may have potential benefits for skin rejuvenation and anti-aging treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 71989-14-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,9,8 and 9 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 71989-14:
(7*7)+(6*1)+(5*9)+(4*8)+(3*9)+(2*1)+(1*4)=165
165 % 10 = 5
So 71989-14-5 is a valid CAS Registry Number.
InChI:InChI=1/C23H25NO6/c1-23(2,3)30-20(25)12-19(21(26)27)24-22(28)29-13-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,24,28)(H,26,27)/t19-/m0/s1
71989-14-5Relevant articles and documents
COMPOUND FOR PREPARATION OF ANTIBODY-PAYLOAD CONJUGATE AND USE THEREOF
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, (2022/03/15)
The present application relates to a novel linker for use in bioconjugation, comprising two or more electrophilic carbon atoms of a carbonyl group, and a click chemistry functional group and, more specifically, to a linker through which a compound, a peptide, and/or a protein can be directly and/or indirectly linked by a substitution reaction to a desired target molecule, that is, a target molecule.
Synthesis of l -octaarginine through microencapsulated palladium-catalyzed allyl ester deprotection
Pérez-López, Ana M.,González-Calderón, Dávir,Occorso, Antonio,Galindo-ángel, Javier,Domínguez-Seglar, José F.,Tamayo, Juan A.,Díaz-Gavilán, Mónica,Gómez-Vidal, José A.
supporting information, p. 2319 - 2322 (2015/08/06)
Octaarginine has been described as a molecular transporter. We report a useful synthesis of orthogonally protected l-octaarginine by using a method based on a microencapsulated palladium catalyst. Known palladium-based methods for allyl ester deprotection have been modified to facilitate purification of the unprotected intermediates. This improvement in the purification step has also been tested with a variety of allyl α-amino esters and allyl α,β-unsaturated esters.
Efficient procedure for the preparation of oligomer-free N-fmoc amino acids
Nowshuddin, Shaik,Rao,Reddy, A. Ram
experimental part, p. 2022 - 2031 (2009/11/30)
A two-step method is presented for the peptide-free, high-purity, and high-yield synthesis of N-Fmoc amino acids. The first step involves the preparation of stable dicyclohexylammonium-amino acid ionic adduct in acetone. Subsequently, the ionic adducts, on reaction with Fmoc-Nosu under mild alkaline conditions, give dipeptide-free N-Fmoc amino acids. The positive charge of the dicyclohexylammonium counterion in the ionic salt has a longer radius, moderating the nucleophilicity of the carboxylate ion of the amino acid and preventing by-products by arresting the formation of mixed anhydrides, the precursors of oligopeptide impurities.
