71257-38-0

Basic information

• Product Name: Pyrrolo[1,2-a]pyrazine, 1,2,3,4-tetrahydro- (9CI)
• Synonyms: Pyrrolo[1,2-a]pyrazine, 1,2,3,4-tetrahydro- (9CI);pyrrolo[1,2-a]pyrazine, 1,2,3,4-tetrahydro-;Albb-009270;1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine(SALTDATA: FREE);1H,2H,3H,4H-pyrrolo[1,2-a]pyrazine
• CAS NO: 71257-38-0
• Molecular Formula: C₇H₁₀N₂
• Molecular Weight: 122.1677
• Product Categories: AMINETERTIARY
• Mol File: 71257-38-0.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 239.6°C at 760 mmHg
• Flash Point: 98.7°C
• Appearance: /
• Density: 1.18g/cm³
• Vapor Pressure: 0.0398mmHg at 25°C
• Refractive Index: 1.628
• Storage Temp.: 2-8°C(protect from light)
• PKA: 7.40±0.20(Predicted)
• CAS DataBase Reference: Pyrrolo[1,2-a]pyrazine, 1,2,3,4-tetrahydro- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrrolo[1,2-a]pyrazine, 1,2,3,4-tetrahydro- (9CI)(71257-38-0)
• EPA Substance Registry System: Pyrrolo[1,2-a]pyrazine, 1,2,3,4-tetrahydro- (9CI)(71257-38-0)

Safety Data

• RIDADR: 3265
• HazardClass: IRRITANT
• PackingGroup: Ⅲ
• Hazardous Substances Data: 71257-38-0(Hazardous Substances Data)

Usage

General Description

Pyrrolo[1,2-a]pyrazine, 1,2,3,4-tetrahydro- (9CI) is a chemical compound that belongs to the pyrazine class of organic compounds. It is a heterocyclic compound containing a pyrazine ring fused to a pyrrole ring. Pyrrolo[1,2-a]pyrazine, 1,2,3,4-tetrahydro- (9CI) is often used as a building block in the synthesis of various pharmaceuticals and agrochemicals. It exhibits potential biological activities and is being studied for its potential use in the development of new drugs. Additionally, it has been found to possess interesting odor properties and is used in the fragrance and flavor industry. Overall, Pyrrolo[1,2-a]pyrazine, 1,2,3,4-tetrahydro- (9CI) is a versatile compound with diverse applications in the fields of chemistry, pharmaceuticals, and fragrance.

InChI:InChI=1/C7H10N2/c1-2-7-6-8-3-5-9(7)4-1/h1-2,4,8H,3,5-6H2

Upstream product

• 29709-35-1 1-(2-aminoethyl)pyrrole 
• 50-00-0 formaldehyd 
• 71257-37-9 3,4-dihydropyrrolo[1,2-a]-pyrazine 

Downstream Products

• 274-45-3 7-azaindolizine 
• 71257-37-9 3,4-dihydropyrrolo[1,2-a]-pyrazine 
• 1416220-64-8 2,2-dimethyl-1-(7-(phenylethynyl)-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)propan-1-one 
• 112758-88-0 1-Benzyl-1,2,3,4-tetrahydropyrrolo<1,2-a>pyrazine 
• 112758-89-1 1-Phenyl-1,2,3,4-tetrahydropyrrolo<1,2-a>pyrazine 
• 112758-87-9 1-Cyclohexyl-1,2,3,4-tetrahydropyrrolo<1,2-a>pyrazine 
• 1174068-78-0 3,4-Dihydro-1H-pyrrolo[1,2-a]pyrazine-2-carboxylic acid tert-butyl ester 
• 165117-99-7 2-acetyl-1,2,3,4-tetrahydropyrrolo-[1,2-a]-pyrazine 
• 165118-06-9 2-benzoyl-1,2,3,4-tetrahydropyrrolo-[1,2-a]-pyrazine 

Relevant articles and documents

Compound as potassium channel modulator

The invention relates to a compound as a potassium channel modulator, which is a compound of a formula (I) or a pharmaceutically acceptable salt thereof. The compound or the pharmaceutically acceptable salt thereof is effective for curing and preventing diseases and symptoms influenced by the activity of potassium ion channels.

PHTHALAZINONE KETONE DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL USE THEREOF

A phthalazinone ketone derivative as represented by formula (I), a preparation method thereof, a pharmaceutical composition containing the derivative, a use thereof as a poly (ADP-ribose) polymerase (PARP) inhibitor, and a cancer treatment method thereof.

Substituted Sulfonamide Compounds

Substituted sulfonamide compounds corresponding to the formula I wherein m, n, p, Q, R1, R2, R3, R4, X, Y and Z have the respective meanings defined herein, pharmaceutical compositions containing such compounds, a process for their preparation, and the use of such compounds for the treatment and/or inhibition of pain and other conditions mediated by bradykinin receptor 1 (B1R) and/or bradykinin receptor 2 (B2R).