70951-85-8

Basic information

• Product Name: 4-bromo-1-tert-butyl-1H-pyrazole
• Synonyms: 4-bromo-1-tert-butyl-1H-pyrazole;4-Bromo-1-t-butylpyrazole;1-tert-Butyl-4-Bromopyrazole;4-Bromo-1-tert-butylpyrazole
• CAS NO: 70951-85-8
• Molecular Formula: C₇H₁₁BrN₂
• Molecular Weight: 203.07964
• Mol File: 70951-85-8.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 229.8±13.0℃ (760 Torr)
• Flash Point: 92.8±19.8℃
• Appearance: /
• Density: 1.37±0.1 g/cm3 (20 ºC 760 Torr)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-bromo-1-tert-butyl-1H-pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-1-tert-butyl-1H-pyrazole(70951-85-8)
• EPA Substance Registry System: 4-bromo-1-tert-butyl-1H-pyrazole(70951-85-8)

Safety Data

• Hazardous Substances Data: 70951-85-8(Hazardous Substances Data)

Usage

General Description

4-bromo-1-tert-butyl-1H-pyrazole is a chemical compound with the molecular formula C7H10BrN2. It is a pyrazole derivative with a bromine atom and a tert-butyl group attached to the nitrogen atom. 4-bromo-1-tert-butyl-1H-pyrazole is commonly used in the pharmaceutical industry as a building block for the synthesis of various drugs and biologically active compounds. It has also been studied for its potential applications in the field of organic chemistry and material science. The unique structure and reactivity of 4-bromo-1-tert-butyl-1H-pyrazole make it a valuable intermediate for the production of a wide range of chemical compounds. As with any chemical substance, proper handling and storage of 4-bromo-1-tert-butyl-1H-pyrazole is essential to ensure safety and prevent any adverse effects on human health and the environment.

Upstream product

• 2075-45-8 4-bromo-1H-pyrazole 
• 75-65-0 tert-butyl alcohol 
• 15754-60-6 N-tert-butylpyrazole 

Downstream Products

• 950858-65-8 1-(tert-butyl)-1H-pyrazole-4-carboxylic acid 
• 1256359-15-5 1-(1,1-dimethylethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 

Relevant articles and documents

FARNESOID X RECEPTOR AGONISTS AND USES THEREOF

Described herein are compounds that are farnesoid X receptor agonists, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with farnesoid X receptor activity.

PYRAZOLYL-SUBSTITUTED HETEROARYLS AND THEIR USE AS MEDICAMENTS

The invention relates to new substituted heteroaryls of formula 1 or of formula 1' wherein A is either N or CH, wherein R2 is selected from the group consisting of -C1-3-alkyl, -C1-3-haloalkyl, F, Br, CI, wherein Y is selected from -O- or -CH2-, and wherein R3 is defined as in claim 1, and the pharmaceutically acceptable salts thereof, and the use of these aforementioned compounds for the treatment of diseases such as asthma, COPD, allergic rhinitis, allergic dermatitis, lupus erythematodes, lupus nephritis and rheumatoid arthritis.

7-(lH-PYRAZOL-4-YL)-1,6-NAPHTHYRIDINE COMPOUNDS AS SYK INHIBITORS

The present invention relates to a compound of formula (I): or a salt thereof; which is an inhibitor of spleen tyrosine kinase (Syk) and therefore potentially of use in treating diseases resulting from inappropriate activation of mast and/or basophil cells, macrophages, and B-cells and related inflammatory responses and tissue damage, for instance inflammatory disease and/or allergic disorders, and in cancer therapy, specifically heme malignancies, chronic spontaneous urticaria and autoimmune conditions.