7081-53-0 Usage
Description
Doxapram hydrochloride monohydrate is a central respiratory stimulant that increases respiration and phrenic nerve activity. It acts through carotid chemoreceptors and is used in formulations to treat patients with chronic pulmonary disease, respiratory depression induced by drug overdose, and to stimulate deep breathing post-anesthesia.
Uses
Used in Pharmaceutical Industry:
Doxapram hydrochloride monohydrate is used as a respiratory stimulant for increasing respiration in patients with chronic pulmonary disease, respiratory depression induced by drug overdose, and to stimulate deep breathing post-anesthesia.
Used in Antibacterial Applications:
Doxapram hydrochloride monohydrate is used as an antibacterial agent to combat bacterial infections.
Clinical Use
Postoperative respiratory depressionAcute respiratory failure
Drug interactions
Potentially hazardous interactions with other drugsAnaesthetics: increased risk of arrhythmias with
volatile liquid general anaesthetics - avoid for at least
10 minutes after volatile liquid general anaesthetics.
Metabolism
Doxapram is extensively metabolised in the liver, and
the major route of excretion of metabolites and a small
amount of unchanged drug is thought to be via bile to the
faeces.
Check Digit Verification of cas no
The CAS Registry Mumber 7081-53-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,0,8 and 1 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 7081-53:
(6*7)+(5*0)+(4*8)+(3*1)+(2*5)+(1*3)=90
90 % 10 = 0
So 7081-53-0 is a valid CAS Registry Number.
InChI:InChI=1/C24H30N2O2.ClH.H2O/c1-2-26-19-22(13-14-25-15-17-28-18-16-25)24(23(26)27,20-9-5-3-6-10-20)21-11-7-4-8-12-21;;/h3-12,22H,2,13-19H2,1H3;1H;1H2
