70672-06-9

Basic information

• Product Name: Benzoic acid, 2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)-, methyl ester
• CAS NO: 70672-06-9
• Molecular Formula: C21H14O5
• Molecular Weight: 346.339
• Mol File: 70672-06-9.mol
• Article Data: 24

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)-, methyl ester(70672-06-9)
• EPA Substance Registry System: Benzoic acid, 2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)-, methyl ester(70672-06-9)

Safety Data

• Hazardous Substances Data: 70672-06-9(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 518-45-6 fluorescein free acid 
• 1624845-20-0 Methyl 2-(3-oxo-6-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)oxy)-3Hxanthen-9-yl)benzoate 
• 153120-93-5 5-amino-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid methyl ester 
• 2321-07-5 fluorescein 
• 74-88-4 methyl iodide 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 136205-88-4 fluorescein methyl ester 
• 53677-99-9 2-(6'-methoxy-3'-oxo-3'H-xanthene-9'-yl)-benzoic acid methyl ester 
• 1227413-23-1 C₂₉H₂₈O₇ 
• 1008363-58-3 methyl 2-(6-(2-bromoethoxy)-3-oxo-3H-xanthen-9-yl) benzoate 
• 1579977-65-3 methyl 2-(3-(3-aminopropoxy)-6-(benzyloxy)-9H-xanthen-9-yl)benzoate 
• 1579977-64-2 methyl 2-(3-(3-aminopropoxy)-6-(prop-2-yn-1-yloxy)-9H-xanthen-9-yl)benzoate 
• 1579977-63-1 methyl 2-(3-(allyloxy)-6-(3-aminopropoxy)-9H-xanthen-9-yl)benzoate 

Relevant articles and documents

A fluorescein-based fluorescence probe for the fast detection of thiol

A new turn-on fluorescent probe for the selective detection of thiol over other amino acids was synthesized. Probe possesses the widely-used thiol-selective 2,4-dinitrobenzenesulfonyl (DNBS) group which can react with thiol and release the fluorescein whi

A highly selective visual detection of tabun mimic diethyl cyanophosphate (DCNP): Effective discrimination of DCNP from other nerve agent mimics

A new tabun specific visual detection protocol is reported. The chemodosimeter fluorescein-hydroxamate aldehyde undergoes tandem nucleophilic substitution followed by cyanohydrin reaction with DCNP and shows a specific spectroscopic behaviour. The probe molecule clearly distinguishes tabun mimic DCNP over other nerve agent simulants as well as strong electrophiles.

Synthesis and Studies of Fluorescein Based Derivatives for their Optical Properties, Urease Inhibition and Molecular Docking

Herein, we design and synthesized new fluorescein based derivatives by insitu formation of fluorescein ester and further treated with corresponding hydrazide and amine to yield respective compounds i.e. FB1, FB2, FB3 and FB4. The spectral purity and chara

Endoplasmic Reticulum Targeting Reactive Oxygen Species Sensor Based on Dihydrofluorescein: Application of Endoplasmic Reticulum Stress

Endoplasmic reticulum (ER) has a unique redox environment, which plays critical roles in the organelle's function and in its pathological responses such as ER stress. In this work, we introduce an ER-targeting fluorogenic reactive oxygen species (ROS) chemosensor (ER-Flu) from copper(I)-catalyzed alkyne-azide cycloaddition of 3-propargyl ester of 2′,7′-dichlorodihydrofluorescein diacetate and N3-glibenclamide, which were adopted as a fluorogenic ROS sensing module and an ER-targeting module, respectively. Thereby, a series of confocal microscopic experiments of ER-Flu demonstrated that the sensor localizes in ER of the live cells and that ROS are elevated in the cells by ER stress inducers such as thapsigargin, brefeldin A, and tunicamycin.

Novel fluorescein derivative compound, process for the preparation thereof and method for detecting zinc (Zn2+) ion using the same

The present invention provides a method for detecting zinc (Zn^2+) ions by synthesizing N-(3andprime;,6andprime;-dihydroxy-3-oxospyro[isoindoline-1,9andprime;-xanthene]-2-yl)-2-hydroxybenzamide, followed by using fluorescent organic nanoparticles obtained through a reprecipitation method. A novel fluorescein derivative compound, a manufacturing method thereof, and a method for detecting zinc ions using the same of the present invention exhibit a very low detection limit (0.0011 andmu;g/ml), are non-toxic, and can detect zinc ions in living cells, thereby being able to be usefully used in biomedical and environmental fields.COPYRIGHT KIPO 2020

Cholesteric fluorescent liquid crystal polysiloxanes with different liquid crystal side chain lengths—Synthesis and properties

With polymethylhydrogensiloxane (PMHS) as the main chain, two series side-chain cholesteric liquid crystal polymers (ChLCPs) with different liquid crystal side chain lengths were prepared by hydrosilylation reaction. Then two series of cholesteric fluorescent liquid crystal polymers (FL-ChLCPs) were obtained by etherification reaction. The obtained FL-ChLCPs have both excellent mesomorphic behavior, and great photoluminescent property. We confirmed their chemical structures by FT-IR, and 1H NMR spectroscopy, and found them with excellent thermal stability by TGA. We characterized their mesomorphic behavior and thermal performance by POM, DSC and XRD, and confirmed all the polymers belonged to cholesteric phase. FL-ChLCPs emitted different-intensity fluorescence under UV light, and we found some regularity by PL spectrum.