698377-66-1

Basic information

• Product Name: (2R)-2-{[(E)-(4-nitrophenyl)methylidene]amino}-2-phenylacetamide
• Synonyms: (2R)-2-{[(E)-(4-nitrophenyl)methylidene]amino}-2-phenylacetamide
• CAS NO: 698377-66-1
• Molecular Weight: 283.287
• Mol File: 698377-66-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R)-2-{[(E)-(4-nitrophenyl)methylidene]amino}-2-phenylacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: (2R)-2-{[(E)-(4-nitrophenyl)methylidene]amino}-2-phenylacetamide(698377-66-1)
• EPA Substance Registry System: (2R)-2-{[(E)-(4-nitrophenyl)methylidene]amino}-2-phenylacetamide(698377-66-1)

Safety Data

• Hazardous Substances Data: 698377-66-1(Hazardous Substances Data)

Upstream product

• 700-63-0 (R)-phenylglycine amide 
• 555-16-8 4-nitrobenzaldehdye 

Downstream Products

• 104-13-2 4-Butylaniline 
• 698378-36-8 (2R)-2-{[(1R)-1-(4-nitrophenyl)-3-butenyl]amino}-2-phenylethanamide 

Relevant articles and documents

Synthesis of enantiopure 1-aryl-1-butylamines and 1-aryl-3-butenylamines by diastereoselective addition of allylzinc bromide to imines derived from (R)-phenylglycine amide

The synthesis of enantiopure 1-aryl-1-butylamines via a highly diastereoselective addition of allylzinc bromide to imines derived from (R)-phenylglycine amide is reported. These are synthesised by a three-step procedure, which involves: (a) formation of the chiral imines; (b) asymmetric addition of the allylzinc reagent; (c) removal of the chiral auxiliary by means of a reductive or non-reductive method. The reductive method provides 1-aryl-1-butylamines whereas the non-reductive method preserves the double bond to afford 1-aryl-3-butenylamines. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.