69822-72-6

Basic information

• Product Name: Toluene-4-sulfonic acid (S)-3-[2-[(1R,3aS,7aR)-1-((R)-5-hydroxy-1,5-dimethyl-hexyl)-7a-methyl-octahydro-inden-(4E)-ylidene]-eth-(Z)-ylidene]-4-methylene-cyclohexyl ester
• Synonyms: Toluene-4-sulfonic acid (S)-3-[2-[(1R,3aS,7aR)-1-((R)-5-hydroxy-1,5-dimethyl-hexyl)-7a-methyl-octahydro-inden-(4E)-ylidene]-eth-(Z)-ylidene]-4-methylene-cyclohexyl ester
• CAS NO: 69822-72-6
• Molecular Weight: 554.835
• Mol File: 69822-72-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Toluene-4-sulfonic acid (S)-3-[2-[(1R,3aS,7aR)-1-((R)-5-hydroxy-1,5-dimethyl-hexyl)-7a-methyl-octahydro-inden-(4E)-ylidene]-eth-(Z)-ylidene]-4-methylene-cyclohexyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Toluene-4-sulfonic acid (S)-3-[2-[(1R,3aS,7aR)-1-((R)-5-hydroxy-1,5-dimethyl-hexyl)-7a-methyl-octahydro-inden-(4E)-ylidene]-eth-(Z)-ylidene]-4-methylene-cyclohexyl ester(69822-72-6)
• EPA Substance Registry System: Toluene-4-sulfonic acid (S)-3-[2-[(1R,3aS,7aR)-1-((R)-5-hydroxy-1,5-dimethyl-hexyl)-7a-methyl-octahydro-inden-(4E)-ylidene]-eth-(Z)-ylidene]-4-methylene-cyclohexyl ester(69822-72-6)

Safety Data

• Hazardous Substances Data: 69822-72-6(Hazardous Substances Data)

Upstream product

• 19356-17-3 25-Hydroxyvitamin D₃ 
• 98-59-9 p-toluenesulfonyl chloride 
• 19356-17-3 calcidiol 

Downstream Products

• 73809-42-4 5,6-trans-1α,25-Dihydroxyvitamin D₃ 3-acetate 
• 73809-41-3 5,6-cis-1α,25-Dihydroxyvitamin D₃ 3-acetate 
• 73837-24-8 5,6-trans-1α,25-Dihydroxyvitamin D₃ 
• 32222-06-3 1α,25-Dihydroxyvitamin D₃ 
• 86823-87-2 (5E)-10,19,25-trihydroxy-10,19-dihydrocholecalciferol 3-acetate 
• 86823-86-1 (5Z)-10,19,25-trihydroxy-10,19-dihydrocholecalciferol 3-acetate 
• 85925-90-2 (5E)-10-oxo-25-hydroxy-19-norcholecalciferol 
• 86852-07-5 (5Z)-10-oxo-25-hydroxy-19-norcholecalciferol 
• 73809-42-4 (5E,7E,1S,3R)-3-acetoxy-9,10-seco-5,7,10⁽¹⁹⁾-cholestatriene-1,25-diol 
• 157637-98-4 (5E,7E,1S,3R,10R)-3-acetoxy-9,10-seco-5,7-cholestadiene-1,25-diol 
• 157637-97-3 (5Z,7E,1S,3R,10R)-3-acetoxy-9,10-seco-5,7-cholestadiene-1,25-diol 
• 157750-01-1 (5E,7E,1S,3R,10S)-3-acetoxy-9,10-seco-5,7-cholestadiene-1,25-diol 
• 157750-00-0 (5Z,7E,1S,3R,10S)-3-acetoxy-9,10-seco-5,7-cholestadiene-1,25-diol 
• 73809-41-3 (5Z,7E,1S,3R)-3-acetoxy-9,10-seco-5,7,10⁽¹⁹⁾-cholestatriene-1,25-diol 

Relevant articles and documents

Novel synthesis of 1α,25-dihydroxy-19-norvitamin D from 25-hydroxyvitamin D

19-Norvitamin D analogs 3a and 3b were synthesized from 25-hydroxyvitamin D, obtained via a bioconversion method. The synthetic route features a highly regio- and stereoselective hydroboration reaction to afford 25-hydroxy-3,5-cyclopropyl-vitamin D deriva

Synthesis, conformational analysis, and biological-activity of the 1-α,25-dihydroxy-10,19-dihydrovitamin D3 isomers

The synthesis of the four 1α,25-dihydroxy-10,19-dihydrovitamin D3 stereoisomers (8-11) is described starting from 25-hydroxyvitamin D3(1c). Acetic acid-catalyzed cycloreversion of 1 α-hydroxylated 3,5-cyclovitamin D compound 14, prod

Direct C(1) Hydroxylation of Vitamin D3 and Related Compounds

A direct synthesis of C(1) hydroxylated vitamin D analogues from the corresponding vitamin D precursors has been developed.Allylic oxidation of 3,5-cyclovitamin D derivatives, readily obtained from the buffered solvolysis of vitamin D tosylates, with selenium dioxide yields 1α-hydroxylated 3,5-cyclovitamin D compounds which are smoothly converted to the desired 1α-hydroxyvitamin D derivatives by acid-catalyzed cycloreversion.Application of this scheme to vitamin D3 (1a), 25-hydroxyvitamin D3 (1b), and vitamin D2 (1c) affords the 1α-hydroxy products in ca.20 percent overall yield.