6963-40-2

Basic information

• Product Name: 2-ethoxyethyl acetoacetate
• Synonyms: 2-ethoxyethyl acetoacetate;3-Oxobutyric acid 2-ethoxyethyl ester;Ai3-06509;Butanoic acid, 3-oxo-, 2-ethoxyethyl ester;Einecs 230-160-9
• CAS NO: 6963-40-2
• Molecular Formula: C₈H₁₄O₄
• Molecular Weight: 174.19436
• EINECS: 230-160-9
• Mol File: 6963-40-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 247.1°C at 760 mmHg
• Flash Point: 102.6°C
• Appearance: /
• Density: 1.039g/cm³
• Vapor Pressure: 0.0261mmHg at 25°C
• Refractive Index: 1.422
• CAS DataBase Reference: 2-ethoxyethyl acetoacetate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ethoxyethyl acetoacetate(6963-40-2)
• EPA Substance Registry System: 2-ethoxyethyl acetoacetate(6963-40-2)

Safety Data

• Hazardous Substances Data: 6963-40-2(Hazardous Substances Data)

Usage

Description

2-Ethoxyethyl acetoacetate, also known as ethyl 3-oxobutanoate and acetoacetic acid ethyl ester, is a colorless liquid chemical compound with a sweet and fruity odor. It is flammable and has the chemical formula C8H14O4. This versatile chemical is commonly used as a solvent in various industrial processes and is also known for its solvency and reactivity.

Uses

Used in Paints and Coatings Industry:
2-Ethoxyethyl acetoacetate is used as a reactive diluent for the production of polyurethane coatings, enhancing the solubility and reactivity of the coating systems.
Used in Adhesives Industry:
It serves as a reactive diluent in the production of polyurethane adhesives, improving the adhesive's performance and bonding capabilities.
Used in Pharmaceutical Industry:
2-Ethoxyethyl acetoacetate is used as a synthetic intermediate in the synthesis of various pharmaceuticals, contributing to the development of new medications.
Used in Agrochemical Industry:
2-ethoxyethyl acetoacetate is utilized as a synthetic intermediate in the production of agrochemicals, aiding in the development of effective crop protection products.
Used in Fragrance Industry:
2-Ethoxyethyl acetoacetate is employed in the synthesis of fragrances, providing unique scents and enhancing the performance of perfumes and scented products.
Used in Coordination Chemistry:
It can act as a ligand in coordination chemistry, playing a role in the formation of coordination compounds and contributing to advances in this field.

InChI:InChI=1/C8H14O4/c1-3-11-4-5-12-8(10)6-7(2)9/h3-6H2,1-2H3

Upstream product

• 674-82-8 4-methyleneoxetan-2-one 
• 110-80-5 2-ethoxy-ethanol 

Downstream Products

• 62760-00-3 2-ethoxyethyl 2-methyl-4-(2-nitrophenyl)-5-ethoxycarbonyl-6-diethoxymethyl-1,4-dihydropyridine-3-carboxylate 
• 142619-07-6 β-ethoxyethyl 2-(m-nitrobenzylidene)acetoacetate 
• 75535-92-1 2-Diethoxymethyl-6-methyl-4-(2-trifluoromethyl-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-(2-ethoxy-ethyl) ester 3-ethyl ester 
• 75206-35-8 4-(2-Cyano-phenyl)-2-diethoxymethyl-6-methyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-(2-ethoxy-ethyl) ester 3-ethyl ester 
• 75530-91-5 2-Cyano-6-methyl-4-(2-trifluoromethyl-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-(2-ethoxy-ethyl) ester 3-ethyl ester 
• 75530-57-3 2-Formyl-6-methyl-4-(2-trifluoromethyl-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-(2-ethoxy-ethyl) ester 3-ethyl ester 
• 75206-46-1 2-Cyano-4-(2-cyano-phenyl)-6-methyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-(2-ethoxy-ethyl) ester 3-ethyl ester 
• 75206-41-6 4-(2-Cyano-phenyl)-2-formyl-6-methyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-(2-ethoxy-ethyl) ester 3-ethyl ester 
• 75206-50-7 4-(2-Cyano-phenyl)-2-hydroxymethyl-6-methyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-(2-ethoxy-ethyl) ester 3-ethyl ester 
• 62760-09-2 2-ethoxyethyl 2-diethoxymethyl-3-ethoxycarbonyl-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-5-carboxylate 
• 62760-56-9 2-ethoxyethyl 2-cyano-3-ethoxycarbonyl-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-5-carboxylate 
• 62760-34-3 2-ethoxyethyl 3-ethoxycarbonyl-2-formyl-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyrimidine-5-carboxylate 
• 62760-79-6 2-ethoxyethyl 3-ethoxycarbonyl-2-hydroxymethyl-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-5-carboxylate 
• 22609-72-9 bis(2-ethoxyethyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate 

Relevant articles and documents

Synthesis and antihypertensive activities of new 1,4-dihydropyridine derivatives containing a nitrooxy moiety at the 3-ester position

The synthesis of a new series of dihydropyridines containing a nitrooxy moiety at the 3-ester position is described. The antihypertensive activity of the compounds was examined and compared with that of nifedipine; some of them were relatively potent. The structure-activity relationship is also discussed.

The influence of the ester function on the vasodilating activity of 1,4-dihydro-2,6-dimethyl-4-nitrophenyl-pyridine-3,5-dicarboxylates

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