69304-45-6 Usage
Description
3,5-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)adenosine is an adenosine nucleoside characterized by the presence of a 1,1,3,3-tetraisopropyl-1,3-disiloxane group attached to the 3' and 5' positions of the adenosine molecule. This unique structure endows it with specific properties that make it a valuable component in the synthesis of nucleic acid analogs and other related compounds.
Uses
Used in Biochemistry Research:
3,5-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)adenosine is used as a building block for the preparation of DNA and RNA duplexes. Its incorporation into these duplexes can enhance their stability and functionality, making it a valuable tool for studying nucleic acid structure and interactions.
Used in Molecular Biology:
In molecular biology, 3,5-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)adenosine is utilized to create duplexes with exonic splicing enhancer activity. This application is particularly relevant in the development of therapeutic strategies targeting RNA splicing, which is a crucial post-transcriptional process involved in the regulation of gene expression.
Used in Drug Development:
The unique properties of 3,5-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)adenosine also make it a potential candidate for the development of novel drugs targeting nucleic acid-based therapeutics. Its ability to form stable duplexes with enhanced activity can be leveraged to design drugs that modulate gene expression or interfere with disease-causing genetic elements.
Used in Nanotechnology:
The structural features of 3,5-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)adenosine can also be exploited in the field of nanotechnology, where it may be used to construct nanoscale devices or materials with specific functions. Its compatibility with nucleic acids and its unique chemical properties make it a promising candidate for such applications.
Check Digit Verification of cas no
The CAS Registry Mumber 69304-45-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,9,3,0 and 4 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 69304-45:
(7*6)+(6*9)+(5*3)+(4*0)+(3*4)+(2*4)+(1*5)=136
136 % 10 = 6
So 69304-45-6 is a valid CAS Registry Number.
69304-45-6Relevant articles and documents
2′-deoxy-2′-α-C-(hydroxymethyl)adenosine as potential anti-HCV agent
Chavain, Natascha,Herdewijn, Piet
experimental part, p. 1140 - 1147 (2011/03/22)
Because of the importance of C-branched nucleosides in the discovery of new antiviral molecules, we decided to synthesize 2′-deoxy-2′-α- C-(hydroxymethyl)adenosine as a potential anti-HCV agent. The synthesis of a new adenosine analogue following two different synthetic routes is described. The new C-branched nucleoside was tested for its antiviral activity and found to be inactive.
