68527-68-4 Usage
Description
5,6-dimethyl-8-nitroquinoline is a chemical compound with the molecular formula C11H10N2O2. It is a nitro-substituted quinoline derivative that is commonly used as a dye intermediate for the production of fluorescent dyes. It is also known for its potential pharmaceutical applications, including its use as an intermediate in the synthesis of pharmaceutical products. This yellow crystalline solid is sparingly soluble in water but soluble in organic solvents. Due to its potential toxic and mutagenic effects, it should be handled with caution in a controlled laboratory setting.
Uses
Used in Dye Industry:
5,6-dimethyl-8-nitroquinoline is used as a dye intermediate for the production of fluorescent dyes, contributing to the creation of various colorants and pigments that are utilized in different applications.
Used in Pharmaceutical Industry:
5,6-dimethyl-8-nitroquinoline is used as an intermediate in the synthesis of pharmaceutical products, playing a crucial role in the development of new medications and therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 68527-68-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,8,5,2 and 7 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 68527-68:
(7*6)+(6*8)+(5*5)+(4*2)+(3*7)+(2*6)+(1*8)=164
164 % 10 = 4
So 68527-68-4 is a valid CAS Registry Number.
InChI:InChI=1/C11H10N2O2/c1-7-6-10(13(14)15)11-9(8(7)2)4-3-5-12-11/h3-6H,1-2H3
68527-68-4Relevant articles and documents
From Anilines to Quinolines: Iodide- and Silver-Mediated Aerobic Double C?H Oxidative Annulation–Aromatization
Wu, Jiwei,Liao, Zhixiong,Liu, Dong,Chiang, Chien-Wei,Li, Zheng,Zhou, Zhonghao,Yi, Hong,Zhang, Xu,Deng, Zixin,Lei, Aiwen
supporting information, p. 15874 - 15878 (2017/10/23)
Quinoline synthesis from easily accessible raw materials such as anilines is a valuable and meaningful task. Herein, we communicate an iodide- and silver-mediated C?H/C?H oxidative annulation–aromatization between anilines and allyl alcohols. This protocol provides a direct route to the synthesis of quinoline derivatives from inexpensive commodities. Various kinds of anilines, even heterocyclic anilines, were shown to be workable substrates, generating the corresponding multi-substituted quinolines in good yields.
