666854-60-0

Basic information

• Product Name: 2,3,4,5-Tetramethyl-1-[2-((4S,5R)-2,2,4-trimethyl-5-phenyl-oxazolidin-3-ylmethyl)-phenyl]-cyclopent-2-enol
• Synonyms: 2,3,4,5-Tetramethyl-1-[2-((4S,5R)-2,2,4-trimethyl-5-phenyl-oxazolidin-3-ylmethyl)-phenyl]-cyclopent-2-enol
• CAS NO: 666854-60-0
• Molecular Weight: 419.607
• Mol File: 666854-60-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,3,4,5-Tetramethyl-1-[2-((4S,5R)-2,2,4-trimethyl-5-phenyl-oxazolidin-3-ylmethyl)-phenyl]-cyclopent-2-enol(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,4,5-Tetramethyl-1-[2-((4S,5R)-2,2,4-trimethyl-5-phenyl-oxazolidin-3-ylmethyl)-phenyl]-cyclopent-2-enol(666854-60-0)
• EPA Substance Registry System: 2,3,4,5-Tetramethyl-1-[2-((4S,5R)-2,2,4-trimethyl-5-phenyl-oxazolidin-3-ylmethyl)-phenyl]-cyclopent-2-enol(666854-60-0)

Safety Data

• Hazardous Substances Data: 666854-60-0(Hazardous Substances Data)

Upstream product

• 3433-80-5 1-Bromo-2-bromomethyl-benzene 
• 492-41-1 (1R,2S)-norephedrine 
• 54458-61-6 2,3,4,5-tetramethyl-2-cyclopenten-1-one 
• 666735-62-2 (4S,5R)-3-(2-Bromo-benzyl)-2,2,4-trimethyl-5-phenyl-oxazolidine 

Relevant articles and documents

A new class of Rh(III) catalyst containing an aminoalcohol tethered to a tetramethylcyclopentadienyl group for asymmetric transfer hydrogenation of ketones

The synthesis and application to asymmetric reduction of acetophenone, of a novel class of Rh(III) catalyst containing a tether between the cyclopentadienyl group and a homochiral aminoalcohol, is described. The complex is a highly active catalyst for asymmetric ketone reduction, however it appears to be unstable to the extended reaction conditions. The well-defined stereochemical structure of the catalyst offers potential for significant improvement and 'fine tuning' towards specific substrates.