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663948-78-5

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663948-78-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 663948-78-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,6,3,9,4 and 8 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 663948-78:
(8*6)+(7*6)+(6*3)+(5*9)+(4*4)+(3*8)+(2*7)+(1*8)=215
215 % 10 = 5
So 663948-78-5 is a valid CAS Registry Number.

663948-78-5Downstream Products

663948-78-5Relevant articles and documents

(4-Piperidinylphenyl)aminoethyl amides as a novel class of non-covalent cathepsin K inhibitors

Kim, Tae-Seong,Hague, Andrew B.,Lee, Tony I.,Lian, Brian,Tegley, Christopher M.,Wang, Xianghong,Burgess, Teresa L.,Qian, Yi-Xin,Ross, Sandra,Tagari, Philip,Lin, Chi-Hwei,Mayeda, Carol,Dao, Jennifer,Jordan, Steven,Mohr, Christopher,Cheetham, Janet,Viswanadhan, Vellarkad,Tasker, Andrew S.

, p. 87 - 90 (2004)

A series of (4-piperidinylphenyl)aminoethyl amides based on dipeptide anilines were synthesized and tested against cathepsin K, cathepsin L and cathepsin B. These new non-covalent inhibitors exhibited single-digit nM inhibition of the cysteine proteases. Compounds 3 and 7 demonstrated potency in both mouse and human osteoclast resorption assays.

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