64339-95-3

Basic information

• Product Name: (+)-DIBENZOYL-L-TARTARIC ANHYDRIDE
• Synonyms: 2,5-Furandione, 3,4-bis(benzoyloxy)dihydro-, (3R,4R)-;(3R,4R)-2,5-Dioxotetrahydrofuran-3,4-diyl dibenzoate
• CAS NO: 64339-95-3
• Molecular Formula: C₁₈H₁₂O₇
• Molecular Weight: 340.28368
• Mol File: 64339-95-3.mol
• Article Data: 16

Chemical Properties

• Melting Point: 174°C
• Boiling Point: 580.0±50.0°C at 760 mmHg (Cal.) ref.
• Flash Point: 215.3±23.6°C (Cal.) ref
• Appearance: /
• Density: 1.5±0.1g/cm3 (Cal.) ref.
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: (+)-DIBENZOYL-L-TARTARIC ANHYDRIDE(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-DIBENZOYL-L-TARTARIC ANHYDRIDE(64339-95-3)
• EPA Substance Registry System: (+)-DIBENZOYL-L-TARTARIC ANHYDRIDE(64339-95-3)

Safety Data

• Hazard Codes: Xi:Irritant
• Statements: R36/37/38:Irritating to eyes, respiratory system and skin.
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S37/39:Wear suitable g
• Hazardous Substances Data: 64339-95-3(Hazardous Substances Data)

Usage

Description

(+)-DIBENZOYL-L-TARTARIC ANHYDRIDE, also known as (3R,4R)-2,5-Dioxotetrahydrofuran-3,4-diyl Dibenzoate, is a derivative compound of Di-O-benzoyl-D-tartaric Acid (D417325). It is a reagent used in the production of chiral salts, which are essential in various chemical and pharmaceutical processes due to their unique properties and applications.

Uses

Used in Pharmaceutical Industry:
(+)-DIBENZOYL-L-TARTARIC ANHYDRIDE is used as a chiral reagent for the synthesis of chiral compounds. Chiral compounds are essential in the development of pharmaceutical drugs, as they often exhibit different biological activities and selectivity compared to their non-chiral counterparts. This makes (+)-DIBENZOYL-L-TARTARIC ANHYDRIDE a valuable tool in the discovery and production of new and improved medications.
Used in Chemical Industry:
(+)-DIBENZOYL-L-TARTARIC ANHYDRIDE is used as a resolving agent for the resolution of racemic mixtures. Racemic mixtures consist of equal amounts of both enantiomers of a chiral compound, which can have different properties and effects. By using (+)-DIBENZOYL-L-TARTARIC ANHYDRIDE, chemists can separate these enantiomers, allowing for the isolation of the desired chiral compound with specific properties.
Used in Research and Development:
(+)-DIBENZOYL-L-TARTARIC ANHYDRIDE is used as a research tool for studying the properties and behavior of chiral compounds. Understanding the unique characteristics of chiral compounds can lead to advancements in various fields, such as materials science, catalysis, and pharmaceuticals. This makes (+)-DIBENZOYL-L-TARTARIC ANHYDRIDE an important compound for scientific exploration and innovation.

Upstream product

• 133-37-9 DL-tartaric acid 
• 98-88-4 benzoyl chloride 
• 87-69-4 L-Tartaric acid 
• 17026-42-5 O,O'-dibenzoyl-D-tartaric acid 
• 2743-38-6 O,O'-dibenzoyl-L-tartaric acid 
• 147-71-7 D-tartaric acid 
• 47464-82-4 di-benzoyltartaric acid 

Downstream Products

• 88009-72-7 C₃₅H₃₄NO₁₀P 
• 88009-72-7 C₃₅H₃₄NO₁₀P 
• 115061-55-7 (2R,3R)-2,3-dibenzoyloxy-3-methoxycarbonylpropanoic acid 
• 88024-20-8 C₂₁H₂₁NO₇ 
• 102921-34-6 C₂₂H₂₁NO₆ 
• 102921-37-9 C₂₂H₁₉NO₈ 
• 102940-21-6 C₂₂H₁₉NO₈ 
• 102921-38-0 C₂₃H₂₁NO₈ 
• 102921-40-4 C₂₄H₂₃NO₈ 
• 102921-40-4 C₂₄H₂₃NO₈ 
• 102921-41-5 C₂₄H₂₃NO₈ 
• 102921-42-6 C₂₅H₂₅NO₈ 
• 102921-43-7 C₂₅H₂₅NO₈ 
• 102921-56-2 (S)-2-((3R,4R)-3,4-Bis-benzoyloxy-2,5-dioxo-pyrrolidin-1-yl)-pentanedioic acid dimethyl ester 

Relevant articles and documents

Iodinanes with Chiral Ligands. Synthesis and Structure of Iodine(III) Dibenzoyl Tartrates

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A L - dibenzoyl tartaric acid for the preparation of dimethyl

The invention belongs to the technical field of chemical synthesis method, in particular to a L - dibenzoyl tartaric acid for the preparation of dimethyl, the L - dibenzoyl tartaric acid for the preparation of dimethyl, comprises the following steps: S1, to L - tartaric acid, benzoyl chloride, thionyl chloride as the raw material, Lewis acid as catalyst, toluene as the solvent, through esterification, Anhydrized reaction, purification L - dibenzoyl tartaric acid [...]; S2, will be L - dibenzoyl tartaric acid [...] in pure water in the hydrolysis to obtain L - dibenzoyl tartaric acid hydrate wet product; S3, L - dibenzoyl tartaric acid hydrate the wet product in methanol and catalyst under the action of the esterification reaction, purify to get the L - dibenzoyl tartaric acid dimethyl ester. The invention the raw materials used are cheap and easy to obtain, mild reaction conditions, to recycle the methanol can be used repeatedly, after treatment is convenient, and is suitable for industrial production, it is worth.

METHOD OF PREPARING (3R,4S)-3-ACETAMIDO-4-ALLYL-N-(TERT-BUTYL)PYRROLIDINE-3-CARBOXAMIDE

A method is provided to conveniently separate racemic (3R,4S)-3-acetamido-4-allyl-N-(tert-butyl)pyrrolidine-3-carboxamide and (3S,4R)-3-acetamido-4-allyl-N-(tert-butyl)pyrrolidine-3-carboxamide using selective crystallization with chiral carboxylic acids.