63877-96-3

Basic information

• Product Name: 2-(4-FLUOROBENZYL)THIOPHENE
• Synonyms: 2-(4-Fluorophenylmethyl)thiophene
• CAS NO: 63877-96-3
• Molecular Formula: C₁₁H₉FS
• Molecular Weight: 192.2561
• Mol File: 63877-96-3.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 264.282°C at 760 mmHg
• Flash Point: 113.634°C
• Appearance: /
• Density: 1.183g/cm³
• Vapor Pressure: 0.016mmHg at 25°C
• Refractive Index: 1.578
• CAS DataBase Reference: 2-(4-FLUOROBENZYL)THIOPHENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-FLUOROBENZYL)THIOPHENE(63877-96-3)
• EPA Substance Registry System: 2-(4-FLUOROBENZYL)THIOPHENE(63877-96-3)

Safety Data

• Hazardous Substances Data: 63877-96-3(Hazardous Substances Data)

Usage

Uses

2-(4-Fluorobenzyl)thiophene can be used to treat leukotriene related pathologies.

InChI:InChI=1/C11H9FS/c12-10-5-3-9(4-6-10)8-11-2-1-7-13-11/h1-7H,8H2

Upstream product

• 1003-09-4 2-bromothiophene 
• 459-57-4 4-fluorobenzaldehyde 
• 3831-29-6 4-fluorobenzyl iodide 
• 188290-36-0 thiophene 
• 15629-92-2 [1,3-bis(diphenylphosphino)propane]dichloronickel(II) 
• 352-11-4 1-chloromethyl-4-fluorobenzene 
• 459-46-1 4-Fluorobenzyl bromide 
• 403-43-0 4-fluorobenzoyl chloride 
• 579-49-7 2-(4-fluorobenzoyl)thiophene 
• 6165-68-0 thiophene boronic acid 

Downstream Products

• 154355-83-6 2-Bromo-5-(4-fluorophenylmethyl)thiophene 
• 154355-88-1 5-((4-fluorophenyl)methyl)-2-iodothiophene 
• 1386262-00-5 C₂₁H₁₈FNO₃S 
• 1386261-89-7 C₁₂H₇FO₃S 
• 1386262-27-6 (Z)-1-ethyl-5'-(4-fluorobenzylidene)-5,6-dimethoxy-5'H-spiro-[indoline-3,2'-thiophen]-2-one 
• 1386261-99-9 C₂₂H₂₀FNO₂S 
• 1386262-26-5 (Z)-1-ethyl-5'-(4-fluorobenzylidene)-4,6-dimethoxy-5'H-spiro-[indoline-3,2'-thiophen]-2-one 
• 1386261-98-8 C₂₂H₂₀FNO₄S 
• 1386261-97-7 C₂₂H₂₀FNO₄S 
• 1386261-96-6 C₂₃H₂₂FNO₅S 
• 1386262-13-0 C₂₂H₂₂FNO₂S 
• 1386262-54-9 (E)-5-(bromo(4-fluorophenyl)methylene)-1-ethyl-5,6-dimethoxy-5'H-spiro[indoline-3,2,-thiophen]-2-one 
• 1386262-53-8 (Z)-5-(bromo(4-fluorophenyl)methylene)-1-ethyl-5,6-dimethoxy-5'H-spiro[indoline-3,2,-thiophen]-2-one 
• 1386262-52-7 (E)-5'-(bromo(4-fluorophenyl)methylene)-1-ethyl-4,5,6-trimethoxy-5'H-spiro[indoline-3,2'-thiophen]-2-one 

Relevant articles and documents

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Process for the preparation of methylene compounds and the novel compound 2-(2,4-Dichloro-5-fluorobenzyl)thiophene

Methylene compounds are preferably prepared by reducing an aluminum halide complex of the formula STR1 in which R1 represents a C6 -C10 -aryl radical which is optionally substituted by 1 to 4 C1 -C4 -alkyl radicals, 1 to 4 fluorine, chlorine and/or bromine atoms, one C1 -C8 -alkoxy group and/or one acetoxy group, or represents a heteroaryl radical which is optionally substituted by one C1 -C4 -alkyl radical and/or one fluorine, chlorine or bromine atom and contains 5 to 10 C atoms and one O or S atom and R2 represents a C1 -C12 -alkyl radical which is optionally substituted by 1 to 5 fluorine, chlorine and/or bromine atoms, independently of R1 represents a radical as defined for R1 and, in the case where R1 =a C6 -C10 -aryl radical which is substituted by 1 to 4 fluorine, chlorine and/or bromine atoms, also represents a furyl or thienyl radical, Y represents fluorine, chlorine or bromine, with an amineborane of the formula STR2 in which R3 represents C1 -C4 -alkyl and R4 represents hydrogen or C1 -C4 -alkyl and/or with sodium borohydride and/or with potassium borohydride. 2-(2,4-Dichloro-5-fluorobenzyl)thiophene is obtainable in this way for the first time.