637-21-8

Basic information

• Product Name: HOMATROPINE HYDROCHLORIDE
• Synonyms: HOMATROPINE HYDROCHLORIDE;homatropineHCl;Homatropinhydrochlorid;(8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 2-hydroxy-2-phenylacetate hydrochloride;(8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 2-hydroxy-2-phenyl-ethanoate hydrochloride;2-hydroxy-2-phenyl-acetic acid (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) ester hydrochloride
• CAS NO: 637-21-8
• Molecular Formula: C16H22ClNO3
• Molecular Weight: 311.8
• EINECS: 211-280-0
• Product Categories: Alkaloids;Biochemistry;Tropane Alkaloids
• Mol File: 637-21-8.mol
• Article Data: 0

Chemical Properties

• Melting Point: 226 °C
• Boiling Point: 403.3°Cat760mmHg
• Flash Point: 197.7°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 3.15E-07mmHg at 25°C
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: Aqueous Base (Slightly), Methanol (Slightly), Water (Slightly)
• Merck: 14,4730
• CAS DataBase Reference: HOMATROPINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: HOMATROPINE HYDROCHLORIDE(637-21-8)
• EPA Substance Registry System: HOMATROPINE HYDROCHLORIDE(637-21-8)

Safety Data

• RIDADR: UN 1544 6.1/PG III
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 637-21-8(Hazardous Substances Data)

Usage

General Description

Homatropine hydrochloride is a medication used to treat certain eye conditions and to reduce excessive salivation and respiratory secretions. It belongs to a class of drugs called anticholinergics, which work by blocking the action of acetylcholine, a neurotransmitter in the body. This helps to dilate the pupils and reduce the production of fluids in the eye, leading to improved vision and decreased discomfort. Homatropine hydrochloride is typically administered as eye drops or ointment and is a commonly used medication in ophthalmology. It may also be used to treat certain symptoms of Parkinson's disease and to reduce coughing. However, it should be used with caution and under the guidance of a healthcare professional due to its potential side effects and interactions with other medications.

InChI:InChI=1/C16H21NO3.ClH/c1-17-12-7-8-13(17)10-14(9-12)20-16(19)15(18)11-5-3-2-4-6-11;/h2-6,12-15,18H,7-10H2,1H3;1H