63693-65-2

Basic information

• Product Name: 1-(4-ISOPROPYLPHENYL)HYDRAZINE
• Synonyms: 1-(4-ISOPROPYLPHENYL)HYDRAZINE;(4-ISOPROPYL-PHENYL)-HYDRAZINE;Hydrazine, [4-(1-methylethyl)phenyl]- (9CI);1-(4-Isopropylphenyl)hydrazine, 90+%;Hydrazine, [4-(1-Methylethyl)phenyl]-;N-(4-Isopropylphenyl)hydrazine
• CAS NO: 63693-65-2
• Molecular Formula: C₉H₁₄N₂
• Molecular Weight: 150.22
• Product Categories: ISOPROPYL
• Mol File: 63693-65-2.mol
• Article Data: 3

Chemical Properties

• Melting Point: 66-69°C
• Boiling Point: 260.1 °C at 760 mmHg
• Flash Point: 128.1 °C
• Appearance: /
• Density: 1.027 g/cm³
• PKA: 5.39±0.20(Predicted)
• CAS DataBase Reference: 1-(4-ISOPROPYLPHENYL)HYDRAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-ISOPROPYLPHENYL)HYDRAZINE(63693-65-2)
• EPA Substance Registry System: 1-(4-ISOPROPYLPHENYL)HYDRAZINE(63693-65-2)

Safety Data

• Statements: 20/21/22
• Safety Statements: 22-36/37/39
• HazardClass: IRRITANT
• Hazardous Substances Data: 63693-65-2(Hazardous Substances Data)

Usage

General Description

1-(4-Isopropylphenyl)hydrazine is a chemical compound with the molecular formula C9H14N2. It is a hydrazine derivative and is often used as a building block in organic synthesis. 1-(4-ISOPROPYLPHENYL)HYDRAZINE is commonly used in the pharmaceutical and chemical industries for the synthesis of various drugs and other organic compounds. It is known for its ability to act as a reagent in the formation of hydrazones and other nitrogen-containing compounds. Additionally, 1-(4-isopropylphenyl)hydrazine has potential applications in the field of medicinal chemistry, as well as in the development of new materials and chemical processes.

InChI:InChI:1S/C9H14N2/c1-7(2)8-3-5-9(11-10)6-4-8/h3-7,11H,10H2,1-2H3

Upstream product

• 118427-29-5 (4-isopropylphenyl)hydrazine hydrochloride 
• 99-88-7 4-Isopropylaniline 

Downstream Products

• 1224734-28-4 2-((2-(4-isopropylphenyl)hydrazinyl)methylene)-1H-indene-1,3(2H)-dione 
• 1246517-81-6 5-(4-fluorophenyl)-1-(4-isopropylphenyl)pyrazolidin-3-one 
• 1246517-80-5 1-(4-isopropylphenyl)-5-phenylpyrazolidin-3-one 
• 1154037-39-4 1-(4-isopropylphenyl)-5-(4-methoxyphenyl)pyrazolidin-3-one 
• 1638238-20-6 5-isopropyl-2,3-diphenyl-1H-indole 
• 5460-67-3 1-isopropyl-4-(phenylsulfonyl)benzene 

Relevant articles and documents

Lewis Acid Catalyzed Annulation of Cyclopropane Carbaldehydes and Aryl Hydrazines: Construction of Tetrahydropyridazines and Application Toward a One-Pot Synthesis of Hexahydropyrrolo[1,2- b]pyridazines

In this report, a facile synthesis of tetrahydropyridazines via a Lewis acid catalyzed annulation reaction of cyclopropane carbaldehydes and aryl hydrazines has been demonstrated. Moreover, the generated tetrahydropyridazine further participated in a cycloaddition reaction with donor-acceptor cyclopropanes to furnish hexahydropyrrolo[1,2-b]pyridazines. We also performed these two steps in one pot in a consecutive manner. In addition, a monodecarboxylation reaction of hexahydropyrrolo[1,2-b]pyridazine was achieved with a good yield.

Synthesis, crystal structure, and fungicidal activity of novel 1,5-Diaryl-1H-pyrazol-3-oxyacetate derivatives

A series of ethyl 2-(1,5-diaryl-1H-pyrazol-3-yloxy)acetate derivatives (5a-5i) have been efficiently synthesized by the reaction of 1,5-diaryl-1H-pyrazol-3-ols (4a-4i) with ethyl 2-bromoacetate. The structures of the newly synthesized compounds were characterized by 1H NMR spectra and elemental analysis, and the crystal structure of the compound ethyl 2-(5-(4-chlorophenyl)-1-phenyl-1H-pyrazol-3-yloxy)acetate (5c) was determined by single crystal X-ray diffraction analysis. The compound 5c belongs to triclinic system with space group P(-1), a = 5.8170(12) A, b = 11.804(2) A, c = 12.783(2) A, α = 83.89(2)°, β = 89.24(3)°, γ = 89.73(3)°, Formula weight: 356.80, Triclinic V = 872.7(3) A3, Dc = 1.358 mg/m3, Z = 2, F (000) = 372. Bioassay results indicated that the compound ethyl 2-(5-(4-fluorophenyl)-1- phenyl-1H-pyrazol-3-yloxy)acetate (5d) exhibited moderate inhibitory activity against Gibberella zeae at the dosage of 10 μg/mL.