63086-28-2

Basic information

• Product Name: 2-(4-MethoxybenzylaMino)acetonitrile
• Synonyms: 2-(4-MethoxybenzylaMino)acetonitrile;[(4-Methoxybenzyl)amino]acetonitrile;4-{[(Cyanomethyl)amino]methyl}anisole
• CAS NO: 63086-28-2
• Molecular Formula: C₁₀H₁₂N₂O
• Molecular Weight: 176
• Mol File: 63086-28-2.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(4-MethoxybenzylaMino)acetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-MethoxybenzylaMino)acetonitrile(63086-28-2)
• EPA Substance Registry System: 2-(4-MethoxybenzylaMino)acetonitrile(63086-28-2)

Safety Data

• Hazardous Substances Data: 63086-28-2(Hazardous Substances Data)

Usage

General Description

2-(4-Methoxybenzylamino)acetonitrile is a chemical compound with the molecular formula C10H12N2O. It is a derivative of acetonitrile and contains a benzylamine moiety with a methoxy substituent. 2-(4-MethoxybenzylaMino)acetonitrile is commonly used in the pharmaceutical industry as a building block in the synthesis of various drugs and pharmaceuticals. It is also used as an intermediate in organic synthesis, particularly in the preparation of biologically active compounds. The presence of the benzylamino group makes it a potentially useful compound in medicinal chemistry for the development of new drugs. However, it is important to handle this chemical with care as it may have toxic and hazardous properties.

Upstream product

• 50-00-0 formaldehyd 
• 151-50-8 potassium cyanide 
• 2393-23-9 4-methoxy-benzylamine 
• 107-14-2 chloroacetonitrile 
• 590-17-0 cyanomethyl bromide 

Downstream Products

• 92636-78-7 (2R,3R)-N-p-methoxybenzyl-N-cyanomethyl-2,3-epoxybutyrylamide 
• 155600-89-8 2-Benzyl-1-oxo-2,7-diaza-spiro[3.5]nonane-7-carboxylic acid tert-butyl ester 
• 808770-74-3 (E)-N-(p-methoxybenzyl)-C-cyanonitrone 
• 808770-74-3 (Z)-N-(p-methoxybenzyl)-C-cyanonitrone 

Relevant articles and documents

METHODS OF TREATING COGNITIVE IMPAIRMENT ASSOCIATED WITH NEURODEGENERATIVE DISEASE

Provided herein are methods of treating cognitive impairment associated with neurodegenerative disease in a patient by administering to the patient an effective amount of the Compound, or a pharmaceutically acceptable salt thereof.

INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL

The present invention provides compounds of Formula I : (I) and the pharmaceutically acceptable salts thereof, which are inhibitors of the ROMK (Kir1.1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and proph

NOVEL INHIBITOR COMPOUNDS OF PHOSPHODIESTERASE TYPE 10A

The present invention relates to compounds of the formula (I), the N-oxides, tautomers, the prodrugs and the pharmaceutically acceptable salts thereof. In formula I the variables Het, A, X, Y, Z, R1, R2, R3, R4, R5 and Q are as defined in the claims. The compounds of the formula I, the N-oxides, tautomers, the prodrugs and the pharmaceutically acceptable salts thereof are inhibitors of phosphodiesterase type 10A. Thus, the invention also relates to the use of the compounds of the formula I, the N-oxides, tautomers, the prodrugs and the pharmaceutically acceptable salts thereof for the manufacture of a medicament and which thus are suitable for treating or controlling of medical disorders selected from neurological disorders and psychiatric disorders, for ameliorating the symptoms associated with such disorders and for reducing the risk of such disorders.