6290-20-6

Basic information

• Product Name: 2-hexyl-1,3-dioxane
• Synonyms: 2-hexyl-1,3-dioxane
• CAS NO: 6290-20-6
• Molecular Formula: C₁₀H₂₀O₂
• Molecular Weight: 172.2646
• EINECS: 228-537-8
• Mol File: 6290-20-6.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 214.3°C at 760 mmHg
• Flash Point: 78.7°C
• Appearance: /
• Density: 0.896g/cm³
• Vapor Pressure: 0.229mmHg at 25°C
• Refractive Index: 1.428
• CAS DataBase Reference: 2-hexyl-1,3-dioxane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-hexyl-1,3-dioxane(6290-20-6)
• EPA Substance Registry System: 2-hexyl-1,3-dioxane(6290-20-6)

Safety Data

• Hazardous Substances Data: 6290-20-6(Hazardous Substances Data)

Usage

General Description

2-hexyl-1,3-dioxane is a chemical compound with the molecular formula C10H20O2. It is a type of dioxane, which is a class of organic compounds with a six-membered ring containing two oxygen atoms. The 2-hexyl-1,3-dioxane is commonly used in the production of cosmetic and personal care products, such as perfumes and lotions, as well as in the formulation of various industrial and household cleaners. It is important to handle this chemical with care, as it may cause irritation to the skin, eyes, or respiratory system if not properly managed. It is also recommended to use this chemical in well-ventilated areas and to wear personal protective equipment, such as gloves and goggles, when handling it. Overall, 2-hexyl-1,3-dioxane is a versatile compound with various applications, but it should be used responsibly to avoid any health and safety risks.

InChI:InChI=1/C10H20O2/c1-2-3-4-5-7-10-11-8-6-9-12-10/h10H,2-9H2,1H3

Upstream product

• 111-71-7 heptanal 
• 504-63-2 trimethyleneglycol 
• 17887-80-8 1,3-bis(trimethylsiloxy)propane 
• 542-69-8 1-iodo-butane 
• 33884-43-4 2-(2-Bromoethyl)-1,3-dioxane 
• 693-04-9 butyl magnesium bromide 
• 91009-06-2 3-hept-1-enyloxy-propan-1-ol 

Downstream Products

• 91179-90-7 3-heptyloxy-propan-1-ol 
• 115-11-7 isobutene 

Relevant articles and documents

Facile SN' Reaction of Alkyl-lithiums with 2-Vinyl-1,3-dioxane

Treatment of 2-vinyl-1,3-dioxane with n-, s-, or t-butyl-lithium in diethyl ether or n-pentane solution results in facile nucleophilic addition of RLi to the carbon-carbon double bond with concomitant cleavage of the ring C-O bond (SN' process) to give high yields of enol ethers having the structure HO3OCH=CHCH2R.

Fe-catalysed Kumada-type alkyl-alkyl cross-coupling. Evidence for the intermediacy of Fe(i) complexes

A novel Fe-NHC catalytic system allows the alkyl-alkyl cross-coupling reaction of alkyl halides and alkylmagnesium reagents has been developed. To our knowledge, this is the first Fe-catalysed Kumada-type coupling for the formation of C(sp3)-C(sp3) bonds in the presence of functional groups. The process takes place under mild conditions, avoiding the formation of β-elimination products. Mechanistic studies suggest the intermediacy of Fe(i) complexes, formed by reduction with the Grignard reagent, as the active species.

Nickel-catalyzed cross-coupling of non-activated and functionalized alkyl halides with alkyl grignard reagents

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