62573-11-9 Usage
Description
PEG10-Tos is a PEG linker containing a hydroxyl group with a tosyl group, which enhances solubility in aqueous media and allows for further derivatization or replacement with other reactive functional groups. The tosyl group serves as an excellent leaving group for nucleophilic substitution reactions, making PEG10-Tos a versatile molecule in various applications.
Uses
Used in Pharmaceutical Industry:
PEG10-Tos is used as a molecular linker for improving the solubility and bioavailability of drugs. The hydrophilic PEG spacer increases the drug's aqueous solubility, while the hydroxyl group allows for further chemical modifications to optimize the drug's properties.
Used in Chemical Synthesis:
PEG10-Tos is used as a versatile building block in chemical synthesis, particularly for the creation of complex molecules and bioconjugates. The hydroxyl group enables the attachment of various functional groups, while the tosyl group acts as a good leaving group for nucleophilic substitution reactions, facilitating the synthesis of diverse molecular structures.
Used in Bioconjugation:
PEG10-Tos is used as a bioconjugation agent to attach biologically active molecules, such as peptides, proteins, or nucleic acids, to other molecules or surfaces. The hydroxyl group allows for the covalent attachment of these biomolecules, while the PEG spacer provides a hydrophilic environment that can reduce non-specific interactions and increase stability.
Used in Drug Delivery Systems:
PEG10-Tos is used as a component in the design of drug delivery systems, such as nanoparticles or liposomes. The hydrophilic PEG spacer can improve the stability and circulation time of these systems in the body, while the hydroxyl group enables the attachment of drugs or targeting moieties to enhance the specificity and efficacy of the delivery system.
Used in Surface Modification:
PEG10-Tos is used for surface modification of materials, such as implants or sensors, to improve their biocompatibility, reduce fouling, or introduce specific functional groups. The hydroxyl group allows for covalent attachment to surfaces, while the PEG spacer provides a hydrophilic barrier that can resist protein adsorption and cell adhesion.
Check Digit Verification of cas no
The CAS Registry Mumber 62573-11-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,2,5,7 and 3 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 62573-11:
(7*6)+(6*2)+(5*5)+(4*7)+(3*3)+(2*1)+(1*1)=119
119 % 10 = 9
So 62573-11-9 is a valid CAS Registry Number.
62573-11-9Relevant articles and documents
A amphiphatic compound containing heterocyclic structure with benzene and nitrogen-atom rings, the preparation method and a surfactant composition containing the compound
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Paragraph 0046-0051, (2019/12/25)
The present invention relates to a novel compound having amphiphilic properties including a benzene ring and a nitrogen ring in a chemical formula, and a method for manufacturing the same. The novel compound of the present invention maintains a sample form for a long time in nucleic acid analysis or blood analysis, thereby being very effective as an active component of a surfactant.COPYRIGHT KIPO 2020
Detergent compounds and compositions
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, (2008/06/13)
Compounds of the formula STR1 wherein R1 and R2 are each straight chain, branched chain or cyclic alkyl, alkenyl, aryl, aralkyl or alkaryl moieties having from 1-30 carbon atoms; R3 is a C2 -C8 alkylene, alkenylene, arylene or alkarylene moiety; R4 is a C1 -C8 alkylene, alkenylene, arylene or alkarylene moiety; A is a water-solubilizing anionic moiety; and n is from 1 to about 100 are useful as surfactants. Compounds wherein groups R1, R2 and R3 and integer n are selectively chosen provide good clay soil detergency performance even in the absence of builders. The compounds are usefully combined with other organic surfactants to provide detergent compositions having good clay and oily soil removal performance.
