62421-33-4

Basic information

• Product Name: Aziridine, 1-[(4-methylphenyl)sulfonyl]-2-propyl-, (R)-
• CAS NO: 62421-33-4
• Molecular Formula: C12H17NO2S
• Molecular Weight: 239.338
• Mol File: 62421-33-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Aziridine, 1-[(4-methylphenyl)sulfonyl]-2-propyl-, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Aziridine, 1-[(4-methylphenyl)sulfonyl]-2-propyl-, (R)-(62421-33-4)
• EPA Substance Registry System: Aziridine, 1-[(4-methylphenyl)sulfonyl]-2-propyl-, (R)-(62421-33-4)

Safety Data

• Hazardous Substances Data: 62421-33-4(Hazardous Substances Data)

Upstream product

• 2013-12-9 D-norvaline 
• 98-59-9 p-toluenesulfonyl chloride 
• 62421-32-3 (R)-2-amino-1-pentanol-bis-p-toluenesulfonate 
• 80696-30-6 (2R)-2-aminopentan-1-ol 

Downstream Products

• 260550-89-8 R-(-)-1-(benzofuran-2-yl)-2-propylaminopentane 
• 354583-03-2 (R)-1-(2-benzofuran-2-yl)-2-N-propyl-p-toluenesulfonylaminopentane 
• 1361969-95-0 (2R,6R)-4-(pentyloxy)-2-propyl-1-tosyl-6-vinyl-1,2,3,6-tetrahydropyridine 
• 1361970-00-4 (2R,6S)-4-(pentyloxy)-2-propyl-1-tosyl-6-vinyl-1,2,3,6-tetrahydropyridine 
• 1361970-08-2 (2R)-2-propyl-1-tosyl-6-vinylpiperidin-4-one 
• 1361970-12-8 (2R,6R)-2-propyl-1-tosyl-6-vinylpiperidin-4-one 
• 1361969-68-7 C₂₁H₃₃NO₃SSi 
• 1361969-69-8 4-methyl-N-((S)-1-(pentyloxy)allyl)-N-((R)-1-(trimethylsilyl)hept-1-yn-4-yl)benzenesulfonamide 
• 1361969-71-2 4-methyl-N-((R)-1-(pentyloxy)allyl)-N-((R)-1-(trimethylsilyl)hept-1-yn-4-yl)benzenesulfonamide 
• 1361969-72-3 C₂₆H₄₁NO₃SSi 
• 1361969-73-4 C₂₆H₄₁NO₃SSi 
• 1361969-88-1 N-((R)-hept-1-yn-4-yl)-4-methyl-N-((S)-1-(pentyloxy)allyl)benzenesulfonamide 
• 1361969-89-2 N-((R)-hept-1-yn-4-yl)-4-methyl-N-((R)-1-(pentyloxy)allyl)benzenesulfonamide 
• 1361969-52-9 (R)-4-methyl-N-(1-(trimethylsilyl)hept-1-yn-4-yl)benzenesulfonamide 

Relevant articles and documents

Stereodefined N,O-acetals: Pd-catalyzed synthesis from homopropargylic amines and utility in the flexible synthesis of 2,6-substituted piperidines

We developed a conceptually new synthetic strategy which exploits the stereochemical information of labile acyclic N,O-acetals. The key to this strategy, chemo- and stereoselective synthesis of N,O-acetals, was achieved by the Pd-catalyzed addition of sulfonyl-protected homopropargylic amines to alkoxyallene. The N,O-acetals generated in this way were combined with Au-catalyzed cycloisomerization to give an access to 2,6-disubstituted piperidines with stereochemical flexibility.

Absolute configuration of insect-produced epilachnene

Samples of (X) and (S)-epilachnene [(5Z)-11-propyl-12-azacyclotetradec-5-en olide] were synthesized from (R) and (S)-norvaline. The diastereomeric α-methoxy-α-trifluoromethylphenylacetyl amides of these synthetic samples, prepared using (S) α-methoxy-α-trifluoromethylphenylacetyl chloride, were well resolved by gas chromatography. Analogous derivatization and gas chromatographic analysis of a sample of epilachnene from the pupal secretion of the coccinellid beetle, Epilachna varivestis, established that the natural product is (S)-epilachnene.