620116-53-2Relevant articles and documents
The intramolecular carboxyarylation approach to podophyllotoxin
Reynolds, Aaron J.,Scott, Andrew J.,Turner, Craig I.,Sherburn, Michael S.
, p. 12108 - 12109 (2007/10/03)
Since 1960, only seven plant-derived anticancer drugs have received FDA approval for commercial production. Two are semisynthetic derivatives of podophyllotoxin. This paper describes concise, highly convergent, and conceptually novel approaches to (-)-pod