619-80-7Relevant articles and documents
Wiberg
, p. 3961,3962 (1953)
Catalysis of the reaction between 4-nitrobenzoic acid and ammonia by boric acid + polyehylene glycol-400
Shteinberg
, p. 1715 - 1717 (2005)
Solvent effect on the synthesis of 4-nitrobenzamide by the reaction of 4-nitrobenzoic acid with ammonia in the presence of the catalytic system constituted by boric acid and polyethylene glycol-400 was studied.
New synthesis of 4-nintrobenzamide
Shteinberg
, p. 972 - 974 (2003)
The reaction of 4-nitrobenzoic acid with ammonia in the presence of various catalysts was studied. Tetrabutoxytitanium and boric acid with addition of PEG-400 favor formation of 4-nitrobenzamide in a high yield. The amidation occurs in the temperature range from 160 to 185°C in trichlorobenzene and in a mixture of trichlorobenzene with o-xylene. Neither PEG-400 nor the above catalysts in the absence of PEG-400 do not catalyze the reaction.
Half-Sandwich Iridium Complexes Based on β-Ketoamino Ligands: Preparation, Structure, and Catalytic Activity in Amide Synthesis
Wang, Yang,Guo, Wen,Guan, Ai-Lin,Liu, Shuang,Yao, Zi-Jian
, p. 11514 - 11520 (2021/07/31)
A series of β-ketoamino-based N,O-chelate half-sandwich iridium complexes with the general formula [Cp*IrClL] have been prepared in good yields. These air-insensitive iridium complexes showed desirable catalytic activity in an amide preparation under mild conditions. A number of amides with diverse substituted groups were furnished in a one-pot reaction with good-to-excellent yields through an amidation reaction of NH2OH·HCl with aldehydes in the presence of these iridium(III) precursors. The excellent catalytic activity, mild reaction conditions, and broad substrate scope gave this type of iridium catalyst potential for use in industry. All of the obtained iridium complexes were well characterized by different spectroscopy techniques. The exact molecular structure of complex 3 has been confirmed by single-crystal X-ray analysis.
Unlocking Amides through Selective C–N Bond Cleavage: Allyl Bromide-Mediated Divergent Synthesis of Nitrogen-Containing Functional Groups
Govindan, Karthick,Chen, Nian-Qi,Chuang, Yu-Wei,Lin, Wei-Yu
supporting information, p. 9419 - 9424 (2021/11/30)
We report a new set of reactions based on the unlocking of amides through simple treatment with allyl bromide, creating a common platform for accessing a diverse range of nitrogen-containing functional groups such as primary amides, sulfonamides, primary amines, N-acyl compounds (esters, thioesters, amides), and N-sulfonyl esters. The method has potential industrial applicability, as demonstrated through gram-scale syntheses in batch and in a continuous flow system.
