6178-44-5

Basic information

• Product Name: Ethyl 3,4,5-trimethoxybenzoate
• Synonyms: RARECHEM AL BI 0063;3,4,5-TRIMETHOXYBENZOIC ACID ETHYL ESTER;ETHYL 3,4,5-TRIMETHOXYBENZOATE;3,4,5-Trimethoxybenzoic;Nsc26825;Benzoic acid, 3,4,5-triMethoxy-, ethyl ester
• CAS NO: 6178-44-5
• Molecular Formula: C₁₂H₁₆O₅
• Molecular Weight: 240.25
• Product Categories: Aromatic Esters
• Mol File: 6178-44-5.mol
• Article Data: 49

Chemical Properties

• Melting Point: 54 °C
• Boiling Point: 168 °C / 6mmHg
• Flash Point: 123.4 °C
• Appearance: /
• Density: 1.113 g/cm³
• Vapor Pressure: 0.00189mmHg at 25°C
• Refractive Index: 1.492
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: Ethyl 3,4,5-trimethoxybenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 3,4,5-trimethoxybenzoate(6178-44-5)
• EPA Substance Registry System: Ethyl 3,4,5-trimethoxybenzoate(6178-44-5)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 6178-44-5(Hazardous Substances Data)

Usage

General Description

Ethyl 3,4,5-trimethoxybenzoate is a chemical compound categorized under the classification of organic compounds known as benzoic acid esters. These are ester derivatives of benzoic acid. It has a role as a plant metabolite. It contains a benzoate ester as part of its structure and is an aromatic ether with the molecular formula C13H18O5. Ethyl 3,4,5-trimethoxybenzoate is often used in several applications and research fields, although it may require appropriate safety measures due to its chemical properties.

InChI:InChI=1/C12H16O5/c1-5-17-12(13)8-6-9(14-2)11(16-4)10(7-8)15-3/h6-7H,5H2,1-4H3

Upstream product

• 1916-07-0 3,4,5-trimethoxybenzoic acid methyl ester 
• 74-83-9 methyl bromide 
• 831-61-8 Ethyl gallate 
• 74-88-4 methyl iodide 
• 64-17-5 ethanol 
• 4521-61-3 3,4,5-Trimethoxybenzoyl chloride 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 3044-56-2 ethyl trimethoxybenzoyl acetate 
• 78-39-7 Triethyl orthoacetate 
• 118-41-2 Eudesmic acid 
• 77-78-1 dimethyl sulfate 
• 186581-53-3 diazomethane 

Downstream Products

• 859076-87-2 1-(2,3,4-trimethoxy-phenyl)-3-(3,4,5-trimethoxy-phenyl)-propane-1,3-dione 
• 99265-10-8 1-phenyl-3-(3,4,5-trimethoxyphenyl)-1,3-propanedione 
• 70452-38-9 4-phenyl-1-(3,4,5-trimethoxy-benzoyl)-thiosemicarbazide 
• 18204-69-8 5-(3,4,5-trimetossifenil)-4-fenil-3-carbossimetiltio-4H-1,2,4-triazolo 
• 91759-76-1 [4-Phenyl-5-(3,4,5-trihydroxy-phenyl)-4H-[1,2,4]triazol-3-ylsulfanyl]-acetic acid 
• 70452-56-1 [4-phenyl-5-(3,4,5-trimethoxy-phenyl)-4H-[1,2,4]triazol-3-ylsulfanyl]-acetic acid ethyl ester 
• 70452-47-0 4-phenyl-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazole-3-thiol 
• 137206-45-2 3,5-bis(3,4,5-trimethoxyphenyl)-1H-1,2,4-triazole 
• 137206-47-4 3-(3,4,5-trimethoxyphenylmethyl)-5-(3,4,5-trimethoxyphenyl)-1,2,4-triazole 
• 137206-48-5 3,4,5-trimethoxyphenyl-β-3,4,5-trimethoxybenzoylamidrazone 
• 137206-51-0 3,4,5-Trimethoxy-benzoic acid N'-[1-imino-2-(3,4,5-trimethoxy-phenyl)-ethyl]-hydrazide 
• 50677-29-7 2-chloromethyl-5-(3,4,5-trimethoxyphenyl)-1,3,4-oxadiazole 
• 75921-68-5 1,2,3-trimethoxy-5-(methoxymethyl)benzene 

Relevant articles and documents

Acyl-functionalized molybdenum compounds [(η3-C3H5)(η5-Cp')Mo(CO)2]: An experimental study including the X-ray structure of a rare endo conformer

A series of new acyl-functionalized molybdenum(II) complexes [(η3-C3H5)(η5-C5H4COR)Mo(CO)2] have been successfully synthesized and crystallographically characterized, and the rel

HCK INHIBITORS FOR THE TREATMENT OF FIBROSIS AND CANCER

Compounds which are thiazole and triazole derivatives are disclosed, including compounds of the following genus: Formula I. The compounds are inhibitors of hematopoietic cell kinase (HCK) and exhibit anti-fibrotic and anti-proliferative effects. They are useful in the treatment of a variety of disorders, including a fibrosis or a fibrotic disease, such as renal fibrosis.

Differences in the Mechanisms of MnO2Oxidation between Lignin Model Compounds with the p-Hydroxyphenyl, Guaiacyl, and Syringyl Nuclei

The purpose of this study was to examine how the rate and mechanism of MnO2 oxidation differ between the p-hydroxyphenyl (H), guaiacyl (G), and syringyl (S) types of simple nonphenolic lignin model compounds as well as the p-ethylphenyl (E) type compounds. The oxidation was conducted using an excess amount of MnO2 in a sulfate buffer solution at a pH value of 1.5 at room temperature. MnO2 oxidized at least the G and S nuclei, although it commonly oxidizes alcohols present at the benzyl position. The oxidation rates of the benzyl alcohol derivatives were in the order of G- > S- ? H- > E-type, which suggests that the rates are determined by the electronic effects of their methoxy and ethyl functional groups on not only their benzyl positions but also their aromatic π-electron systems. The kinetic isotope effect was observed in the MnO2 oxidations of the same derivatives deuterated at their benzyl hydroxymethyl groups. The observed magnitudes were in the order of E- ? H- > G- ? S-type, suggesting that the contribution of oxidation of their aromatic nuclei, which is another reaction mode of the oxidation of their benzyl positions, increases in the reverse order.