615-41-8 Usage
Description
1-Chloro-2-iodobenzene is an organic compound with the chemical formula C6H4ClI, featuring a chlorine atom at the 1st position and an iodine atom at the 2nd position on a benzene ring. It is a clear, colorless to light yellow liquid and is known for its reactivity and use as a building block in the synthesis of various organic compounds.
Uses
1. Used in Pharmaceutical Industry:
1-Chloro-2-iodobenzene is used as a reactant for the synthesis of biaryl derivatives of seasamol, which are known for their antioxidant activity against DPPH radicals. This application is particularly relevant in the development of new drugs and pharmaceutical compounds.
2. Used in Chemical Synthesis:
1-Chloro-2-iodobenzene serves as a precursor in the preparation of various organic compounds, such as 2,2'-dichloro-biphenyl, N,N-diaryl-o-phenylenediamines, and 4(5)-(2-chlorophenyl)-1H-imidazole. These compounds have diverse applications in different industries, including pharmaceuticals, materials science, and chemical research.
3. Used in Material Science:
In the field of material science, 1-chloro-2-iodobenzene is involved in the synthesis of novel compounds with potential applications in various areas, such as electronics, coatings, and polymers.
4. Used in Research and Development:
1-Chloro-2-iodobenzene is also utilized in research and development for the exploration of new chemical reactions and the synthesis of innovative organic compounds with potential applications in various industries.
General Description:
1-Chloro-2-iodobenzene is a versatile organic compound that reacts with lanthanum metal in the presence of trimethylchlorosilane to yield 1-chloro-2-trimethylsilylbenzene, further demonstrating its utility in chemical synthesis and research.
Check Digit Verification of cas no
The CAS Registry Mumber 615-41-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,1 and 5 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 615-41:
(5*6)+(4*1)+(3*5)+(2*4)+(1*1)=58
58 % 10 = 8
So 615-41-8 is a valid CAS Registry Number.
InChI:InChI=1/C6H4ClI/c7-5-3-1-2-4-6(5)8/h1-4H
615-41-8Relevant articles and documents
Simple preparation of high-quality graphene flakes without oxidation using potassium salts
Kwon, Jiyoung,Lee, Sun Hwa,Park, Kwang-Hyun,Seo, Dong-Hwa,Lee, Jinsup,Kong, Byung-Seon,Kang, Kisuk,Jeon, Seokwoo
, p. 864 - 868 (2011)
Preparation of graphene flakes without oxidation is important to preserve the superb intrinsic properties of graphene. A new and simple route to produce few-layer, flake-type graphene with minimized oxidation (2%) by the intercalation of potassium into raw graphite using potassium salts is proposed. Copyright
Dehydroxyalkylative halogenation of C(aryl)-C bonds of aryl alcohols
Liu, Mingyang,Zhang, Zhanrong,Liu, Huizhen,Wu, Tianbin,Han, Buxing
supporting information, p. 7120 - 7123 (2020/07/14)
We herein report Cu mediated side-directed dehydroxyalkylative halogenation of aryl alcohols. C(aryl)-C bonds of aryl alcohols were effectively cleaved, affording the corresponding aryl chlorides, bromides and iodides in excellent yields. Aryl alcohols could serve as both aromatic electrophilic and radical synthetic equivalents during the reaction.
Functional Group Transposition: A Palladium-Catalyzed Metathesis of Ar-X σ-Bonds and Acid Chloride Synthesis
De La Higuera Macias, Maximiliano,Arndtsen, Bruce A.
supporting information, p. 10140 - 10144 (2018/08/23)
We describe the development of a new method to use palladium catalysis to form functionalized aromatics: via the metathesis of covalent σ-bonds between Ar-X fragments. This transformation demonstrates the dynamic nature of palladium-based oxidative addition/reductive elimination and offers a straightforward approach to incorporate reactive functional groups into aryl halides through exchange reactions. The reaction has been exploited to assemble acid chlorides without the use of high energy halogenating or toxic reagents and, instead, via the metathesis of aryl iodides with other acid chlorides.
