6149-23-1

Basic information

• Product Name: 1H-Indene-1,3(2H)-dione, 2-(3-methoxyphenyl)-
• CAS NO: 6149-23-1
• Molecular Formula: C16H12O3
• Molecular Weight: 252.269
• Mol File: 6149-23-1.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 1H-Indene-1,3(2H)-dione, 2-(3-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indene-1,3(2H)-dione, 2-(3-methoxyphenyl)-(6149-23-1)
• EPA Substance Registry System: 1H-Indene-1,3(2H)-dione, 2-(3-methoxyphenyl)-(6149-23-1)

Safety Data

• Hazardous Substances Data: 6149-23-1(Hazardous Substances Data)

Usage

Chemical class

Indene-1,3-dione derivatives

Usage

Organic synthesis, pharmaceutical research

Potential biological activities

Anticancer, antimicrobial, anti-inflammatory

Potential applications

Synthesis of heterocyclic compounds

Properties

1H-Indene structure, 3(2H)-dione functional group, 2-(3-methoxyphenyl) substituent.

Upstream product

• 553-86-6 benzofuran-2(3H)-one 
• 591-31-1 3-methoxy-benzaldehyde 
• 17910-70-2 3-(3-methoxy-benzylidene)-3H-isobenzofuran-1-one 
• 87-41-2 2-benzofuran-1(3H)-one 

Relevant articles and documents

1,3-DI-OXO-INDENE DERIVATIVE, PHARMACEUTICALLY ACCEPTABLE SALT OR OPTICAL ISOMER THEREOF, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS AN ANTIVIRAL, ACTIVE INGREDIENT

The present invention relates to 1,3-dioxoindene derivatives, pharmaceutically acceptable salts or optical isomers thereof, a preparation method for same, and a pharmaceutical composition containing same as an active ingredient with antiviral activity. Th

INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS

The invention relates to indanone/indandione derivatives and heterocyclic analogs of Formula (I) wherein Ar1, A, B, L1, Y, Z, and (R1)n n are as described in the description; to pharmaceutically acceptable salts thereof, and to the use of such compounds as medicaments, especially as NPS receptor antagonists.

Reactions of Carbonyl Compounds in Basic Solutions. Part 9. Methoxide-catalysed Cyclization of Benzylidenephthalides and Methyl o-Phenylacetylbenzoates

The detailed mechanism of the methoxide-catalysed rearrangement of substituted benzylidenephthalides and both normal and pseudo methyl o-phenylacetylbenzoates to form 2-phenylindane-1,3-diones has been studied.A rate-acidity function correlation for the reactions in methanolic dimethyl sulphoxide (DMSO) shows a linear increase in rate with increasing H- to reach a maximum in rate before decreasing, except for the p-nitro substrate.This derivative shows a rate decrease throughout the H- range.The ρ values in methanol and in 94 mol percent methanolic DMSO are 1.7 and -1.6, respectively.The kinetic isotope effect has been observed with kH/kD 0.8-1.0.The equilibrium constants for ring-chain tautomerism of the methyl o-phenylacetylbenzoates have been determined and shown to be independent of substituent and solvent composition.The rate-determining step is the intramolecular attack of the anion of the normal ester on the ester carbonyl group.In methanol and methanolic DMSO of high methanol content this is preceded by the ionization equilibrium of the normal ester.In methanolic DMSO of low methanol content and for the p-nitro substrate, the initial state is the anion itself.