61243-05-8

Basic information

• Product Name: 1,2-Ethanediol, 1-(2-furanyl)-, (1S)-
• Synonyms: S-2-(1,2-Dihydroxyethyl)furan;(1S)-(2-furyl)ethane-1,2-diol;1-(2'-furyl)ethan-1S,2-diol;(S)-1-(furan-2-yl)ethane-1,2-diol;1-(2-furyl)-1,2-ethanediol
• CAS NO: 61243-05-8
• Molecular Formula: C6H8O3
• Molecular Weight: 128.12600
• Mol File: 61243-05-8.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: 1,2-Ethanediol, 1-(2-furanyl)-, (1S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Ethanediol, 1-(2-furanyl)-, (1S)-(61243-05-8)
• EPA Substance Registry System: 1,2-Ethanediol, 1-(2-furanyl)-, (1S)-(61243-05-8)

Safety Data

• Hazardous Substances Data: 61243-05-8(Hazardous Substances Data)

Upstream product

• 1487-18-9 (furan-2-yl)ethylene 
• 19377-75-4 1-(furan-2-yl)ethane-1,2-diol 
• 100-52-7 benzaldehyde 
• 17678-19-2 2-(2-hydroxyacetyl)furan 
• 1040427-99-3 (R)-furan-2-yl-hydroxyacetic acid butyl ester 
• 98-01-1 furfural 
• 13265-84-4 D-glucal 
• 14086-08-9 (R)-2-(2-furyl)-1,2-ethanediol 
• 138514-70-2 peracetyl-L-glucosyl bromide 
• 2873-29-2 3,4,6-tri-O-acetyl-1,5-anhydro-2-deoxy-L-arabino-hex-1-enitol 
• 1578-26-3 1-(2'-furyl)-2-trimethylsilanylethan-1-ol 
• 381164-73-4 Benzoic acid (S)-1-furan-2-yl-2-hydroxy-ethyl ester 
• 13170-43-9 (trimethylsilyl)methylmagnesium chloride 
• 14086-10-3 C₂₀H₁₆O₅ 

Downstream Products

• 948047-91-4 (S)-2-(furan-2-yl)-2-hydroxyethyl 4-methylbenzenesulfonate 
• 120269-55-8 Benzoic acid (S)-6-hydroxy-3-oxo-3,6-dihydro-2H-pyran-2-ylmethyl ester 
• 254104-03-5 (2R,3S,4R,5R)-1-tosyl-3,4,5-triacetoxy-2-phenylmethoxymethyl piperidine 
• 254104-01-3 (2R,3S,4S,5S)-1-tosyl-3,4,5-triacetoxy-2-phenylmethoxymethyl piperidine 
• 254104-00-2 (2R,3R)-1-tosyl-4,5-dihydroxy-2-phenylmethoxymethyl-3-piperidyl acetate 
• 254104-04-6 (2R,3S,4R,5R)-1-tosyl-3,4,5-triacetoxy-2-hydroxymethyl piperidine 
• 254104-02-4 (2R,3S,4S,5S)-1-tosyl-3,4,5-triacetoxy-2-hydroxymethyl piperidine 
• 254103-98-5 (2R,3R,6S)-1-tosyl-6-ethoxy-2-phenylmethoxymethyl-1,2,3,6-tetrahydro-3-pyridyl acetate 
• 254103-97-4 (2R,3R,6S)-1-tosyl-6-ethoxy-2-phenylmethoxymethyl-1,2,3,6-tetrahydropyridin-3-ol 
• 254103-99-6 (2R,3R)-1-tosyl-2-phenylmethoxymethyl-1,2,3,6-tetrahydro-3-pyridyl acetate 
• 254103-96-3 (R)-2-((1-triazo-2-phenylmethoxy)ethyl)furan 
• 249284-71-7 (2R,6S)-1,6-dihydro-1-tosyl-6-ethoxy-2-phenylmethoxymethyl-3(2H)-pyridinone 
• 249284-70-6 (2R,6S)-1,6-dihydro-1-tosyl-6-hydroxy-2-phenylmethoxymethyl-3(2H)-pyridinone 
• 219715-78-3 (R)-N-[1'-(2-Furyl)-2'-benzyloxyethyl]toluene-p-sulfonamide 

Relevant articles and documents

Method for synthesizing chiral 1,2-diol compound

The invention relates to a method for synthesizing a chiral 1,2-diol compound, which comprises the following steps: sequentially adding a cobalt catalyst, a ligand, alpha-hydroxy ketone, an organic solvent and silane into a reaction system at 20-30 DEG C in a nitrogen atmosphere, then stirring the mixture, and carrying out column chromatography separation on the obtained product to obtain the chiral 1,2-diol compound. The high-yield cobalt catalyst in the earth crust is used, meanwhile, cheap silane (PMHS, 500 g/298 yuan) is used as a reducing agent, the asymmetric reduction reaction of alpha-hydroxy ketone can be efficiently achieved under the mild condition, and the chiral 1,2-diol compound with high yield and optical activity is obtained. Moreover, through the creative labor of the inventor, the reaction yield can reach 99%, and meanwhile, the content of the target product in the generated reaction product is 99% (namely, the yield is 99%, 99% ee).

Catalytic and highly enantioselective Friedel-Crafts type reactions of heteroaromatic compounds with trifluoropyruvate and glyoxylate by a dicationic palladium complex

The highly enantioselective Friedel-Crafts alkylation of furan and thiophene derivatives with trifluoropyruvate, which have never provided the high level of asymmetric induction and yield until now, was achieved by using dicationic palladium complexes as Lewis acid catalysts. Moreover, glyoxylate instead of trifluoropyruvate as an electrophile led to complete change of regioselectivity with 2-trimethylsilylated furan, thiophene, and pyrrole derivatives to give the corresponding heteroarylated products in high yields and enantioselectivities. The respective products with trifluoropyruvate and glyoxylate could also be obtained via sequential catalytic reaction; intramolecular cyclization of alkynyldiols using cationic Au catalyst followed by Friedel-Crafts type reactions using dicationic Pd catalyst.

Organic metal compound and process for preparing optically-active alcohols using the same

The present invention provides an asymmetric reduction catalyst effective in preparing optically-active alcohol compounds having various functional groups, and a process for preparing optically-active alcohol compounds using said asymmetric reduction catalyst. The organic metal compound of the present invention is represented by the following general formula (1): wherein R1 and R2 may be mutually identical or different, and are an alkyl group, a phenyl group, a naphthyl group, a cycloalkyl group, or an alicyclic ring formed by binding R1 and R2, which may have a substituent; R3 is a hydrogen atom or an alkyl group; Cp is a cyclopentadienyl group, which may have a substituent, bound to M1 via a π bond; X1 is a halogen atom or a hydrido group; M1 is rhodium or iridium; and * denotes asymmetric carbon.