6097-26-3

Basic information

• Product Name: 4-METHOXYPHENACYL THIOCYANATE
• Synonyms: 2-(4-METHOXYPHENYL)-2-OXOETHYL THIOCYANATE;4-METHOXYPHENACYL THIOCYANATE;4-METHOXYPHENACYL THIOCYANATE, 95+%;2-(cyanosulfanyl)-1-(4-Methoxyphenyl)ethan-1-one
• CAS NO: 6097-26-3
• Molecular Formula: C₁₀H₉NO₂S
• Molecular Weight: 207.25
• Mol File: 6097-26-3.mol
• Article Data: 36

Chemical Properties

• Melting Point: 125-127
• Boiling Point: 395.6 °C at 760 mmHg
• Flash Point: 193.1 °C
• Appearance: /
• Density: 1.227 g/cm³
• Vapor Pressure: 1.81E-06mmHg at 25°C
• Refractive Index: 1.571
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4-METHOXYPHENACYL THIOCYANATE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-METHOXYPHENACYL THIOCYANATE(6097-26-3)
• EPA Substance Registry System: 4-METHOXYPHENACYL THIOCYANATE(6097-26-3)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22-43
• Safety Statements: 36/37
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 6097-26-3(Hazardous Substances Data)

Usage

General Description

4-Methoxyphenacyl Thiocyanate, also known as C11H9NO2S, is an organic chemical compound. It includes elements such as carbon, hydrogen, nitrogen, oxygen, and sulfur. 4-METHOXYPHENACYL THIOCYANATE, primarily relevant in the field of chemistry, is known for its use in synthesizing other chemicals. It features a thiocyanate functional group, typically characterized by the linkage of sulfur, carbon, and nitrogen atoms. The details about its physical properties, toxicity, or specific usages are not widely available, indicating it may not be a widely-used or well-researched compound.

InChI:InChI=1/C10H9NO2S/c1-13-9-4-2-8(3-5-9)10(12)6-14-7-11/h2-5H,6H2,1H3

Upstream product

• 6832-17-3 2-diazo-1-(4-methoxyphenyl)ethanone 
• 333-20-0 potassium thioacyanate 
• 51747-42-3 2-(4-methoxy-phenyl)-acrylic acid 
• 1147550-11-5 ammonium thiocyanate 
• 768-60-5 4-methoxyphenylacetylen 
• 163276-49-1 1-thiocyanatopyrrolidine-2,5-dione 
• 637-69-4 4-Methoxystyrene 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 2632-13-5 2-Bromo-4'-methoxyacetophenone 
• 540-72-7 sodium thiocyanide 
• 344790-87-0 1-butyl-3-methylimidazolium thiocyanate 
• 532-55-8 Benzoyl isothiocyanate 
• 2196-99-8 2-chloro-1-(4-methoxyphenyl)ethanone 
• 15192-76-4 copper(II) thiocyanate 

Downstream Products

• 2104-05-4 4-(4-methoxyphenyl)thiazole-2(3H)-thione 
• 2104-03-2 4-(4-methoxyphenyl)-2-oxo-thiazole 
• 2104-01-0 2-chloro-4-(4-methoxy-phenyl)-thiazole 
• 128533-75-5 Acetic acid N'-[2-(4-methoxy-phenyl)-2-oxo-1-thiocyanato-eth-(E)-ylidene]-N-p-tolyl-hydrazide 
• 128533-74-4 Acetic acid N'-[2-(4-methoxy-phenyl)-2-oxo-1-thiocyanato-eth-(E)-ylidene]-N-phenyl-hydrazide 
• 76488-04-5 2-[2-Imino-4-(4-methoxy-phenyl)-thiazol-3-yl]-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid ethyl ester 
• 76487-99-5 1-(4-Methoxy-phenyl)-6,7,8,9-tetrahydro-3,10-dithia-4,10b-diaza-cyclopenta[a]fluoren-5-one 
• 256661-33-3 5-formyl-2-morpholino-4-(4-hydroxyphenyl)thiazole 
• 256661-31-1 5-formyl-2-morpholino-4-(4-methoxyphenyl)thiazole 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 959-23-9 4'-methoxychalcone 
• 256661-25-3 2-morpholino-4-(4-methoxyphenyl)thiazole 
• 79576-73-1 C₂₀H₁₆N₂O₂S₃ 
• 343799-14-4 2-{2-[2-(4-Methoxy-phenyl)-2-oxo-ethyl]-isothioureido}-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid ethyl ester 

Relevant articles and documents

Visible-Light-Mediated Additive-Free Decarboxylative Ketonization Reaction of Acrylic Acids: An Access to α-Thiocyanate Ketones

Visible-light-mediated additive-free decarboxylative functionalization of acrylic acids has been developed. The reaction uses inexpensive organic dye 9,10-dicyanoanthracene as a photocatalyst and uses the ubiquitous dioxygen as both an oxygen source and an oxidant. Through this mild and environmentally friendly method, a series of important α-thiocyanate ketones can be generated from easily available acrylic acids and ammonium thiocyanate. In addition, the facile transformation of product α-thiocyanate ketones makes this method have great potential for application in organic and pharmaceutical chemistry.

An ionic liquid supported on magnetite nanoparticles as an efficient heterogeneous catalyst for the synthesis of alkyl thiocyanates in water

The present study describes a convenient method to synthesize alkyl thiocyanates from alkyl halides with the use of a novel nanomagnetic-supported organocatalyst (MNP@PEG-ImCl). The new supported ionic liquid is fully characterized by field-emission scanning electron microscopy (FESEM), Fourier-transform infrared (FT-IR), energy dispersive X-ray analysis (EDAX), X-ray powder diffraction (XRD), transmission electron microscopy (TEM), vibrating sample magnetometry (VSM) as well as thermogravimetric analysis (TGA) techniques. It is noteworthy that we observed easy separation of the catalyst from the reaction mixture by a simple magnetic decantation and its reutilization many times without any appreciable loss of activities.

Photo-sensitized oxy-thiocyanation of terminal alkynes/1,3-aryldienes and their one-pot conversion to 2-hydroxy 4-substituted aryl thiazoles

A regioselective visible light induced synthesis of aryl α-thiocyano ketones/thiocyano alcohols from activated terminal aryl alkynes and aryl 1,3-conjugated dienes was achieved. This mild and non-metallic oxidation is exclusively driven by benign ambient air in the presence of an organic photo-catalyst and NH4SCN. This protocol was also demonstrated at the 5 mmol scale for the synthesis of potentially therapeutic 2-hydroxy 4-substituted arylthiazoles in good yields, signifying its amenability for large-scale application.