604010-60-8 Usage
Description
(Z)-2-(4-(1,2-diphenylbuta-1,3-dien-1-yl)phenoxy)-N,N-dimethylethanamine, commonly known as fluoxetine, is a widely prescribed medication that belongs to the class of selective serotonin reuptake inhibitors (SSRIs). It is characterized by its ability to increase the levels of serotonin, a neurotransmitter in the brain, which plays a crucial role in regulating mood, sleep, appetite, and energy levels. (Z)-2-(4-(1,2-diphenylbuta-1,3-dien-1-yl)phenoxy)-N,N-dimethylethanamine is known for its effectiveness in treating various mental health disorders and has been in use since the 1980s.
Uses
Used in Pharmaceutical Industry:
Fluoxetine is used as an antidepressant for the treatment of depression, obsessive-compulsive disorder, panic disorder, and bulimia. Its mechanism of action involves the selective inhibition of serotonin reuptake, leading to an increase in the availability of serotonin in the synaptic cleft and consequently improving mood and other related symptoms.
Used in Treatment of Premenstrual Dysphoric Disorder:
Fluoxetine is also utilized in the treatment of premenstrual dysphoric disorder (PMDD), a severe form of premenstrual syndrome. It helps alleviate the emotional and physical symptoms associated with PMDD by modulating serotonin levels.
Used in Capsule or Liquid Form:
Fluoxetine is available in the form of a capsule or liquid, providing flexibility in administration and catering to the needs of different patients. It is typically taken once daily, either in the morning or evening, and may require several weeks to show noticeable improvements.
Side Effects and Tolerability:
While fluoxetine may cause side effects such as nausea, diarrhea, insomnia, and sexual problems, it is generally well-tolerated by patients. The benefits of the medication often outweigh the potential side effects, making it a popular choice for the treatment of various mental health conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 604010-60-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,0,4,0,1 and 0 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 604010-60:
(8*6)+(7*0)+(6*4)+(5*0)+(4*1)+(3*0)+(2*6)+(1*0)=88
88 % 10 = 8
So 604010-60-8 is a valid CAS Registry Number.
604010-60-8Relevant articles and documents
Oxidative heck arylation for the stereoselective synthesis of tetrasubstituted olefins using nitroxides as oxidants
He, Zhiheng,Kirchberg, Sylvia,Froehlich, Roland,Studer, Armido
supporting information; experimental part, p. 3699 - 3702 (2012/05/20)
One, two, and three! Nitroxides and dioxygen serve as oxidants in highly stereoselective oxidative Pd-catalyzed Heck arylations in which aryl boronic acids are used to synthesize triarylalkyl-substituted olefins. The reactions occur under very mild conditions at room temperature. As an example, the threefold sequential arylation of methyl acrylate is the crucial step in the stereoselective synthesis of Z-Tamoxifen.
(Z)-tamoxifen and tetrasubstituted alkenes and dienes via a regio- and stereospecific three-component magnesium carbometalation palladium(O) cross-coupling strategy
Tessier, Pierre E.,Penwell, Andrea J.,Souza, Fabio E. S.,Fallis, Alex G.
, p. 2989 - 2992 (2007/10/03)
(Matrix presented) The synthesis of various tetrasubstituted alkenes and dienes in a regio- and stereocontrolled manner is described. This three-component coupling strategy involves the addition of Grignard reagents to propargyl alcohols followed by palladium(O)-mediated cross-coupling with aryl or vinyl halides. This protocol has been applied to the synthesis of (Z)-Tamoxifen and related mimics.
