60086-36-4

Basic information

• Product Name: Benzoic acid, 4-fluoro-2-(phenylthio)-
• CAS NO: 60086-36-4
• Molecular Formula: C13H9FO2S
• Molecular Weight: 248.278
• Mol File: 60086-36-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 4-fluoro-2-(phenylthio)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-fluoro-2-(phenylthio)-(60086-36-4)
• EPA Substance Registry System: Benzoic acid, 4-fluoro-2-(phenylthio)-(60086-36-4)

Safety Data

• Hazardous Substances Data: 60086-36-4(Hazardous Substances Data)

Upstream product

• 2252-51-9 2-choro-4-fluorobenzoic acid 
• 108-98-5 thiophenol 
• 1006-41-3 2-bromo-4-fluorobenzoic acid 

Relevant articles and documents

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We report herein, a silver(i)-catalyzed Smiles rearrangement of 2-aryloxy- or 2-(arylthio)benzoic acids to provide aryl-2-hydroxybenzoate or aryl-2-mercaptobenzoate dimer, respectively, through 1,5-aryl migration from oxygen or sulfur to carboxylate oxygen. Mechanistically, the aryl ether moiety undergoes an intramolecular ipso attack by the carboxyl radical followed by a C-O or C-S bond cleavage. Aryl-2-mercaptobenzoates undergo oxidative dimerization through a thiol moiety in situ.

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